High-risk variants of cutaneous squamous cell carcinoma in patients with discoid lupus erythematosus: a case series

Cutaneous squamous cell carcinoma, the second most common form of non-melanotic skin cancer, may develop in long-standing discoid lesions, especially those that are depigmented and located in sun-exposed areas. The clinical course of this complication may be aggressive, with early metastases and a r...

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Veröffentlicht in:Lupus 2013-06, Vol.22 (7), p.736-739
Hauptverfasser: Flower, C, Gaskin, D, Bhamjee, S, Bynoe, Z
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creator Flower, C
Gaskin, D
Bhamjee, S
Bynoe, Z
description Cutaneous squamous cell carcinoma, the second most common form of non-melanotic skin cancer, may develop in long-standing discoid lesions, especially those that are depigmented and located in sun-exposed areas. The clinical course of this complication may be aggressive, with early metastases and a risk of mortality. We report three cases demonstrating this emerging trend of secondary squamous cell carcinoma in discoid lesions as the incidence of this secondary malignancy in other diseased skin lesions is on the decline.
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source MEDLINE; SAGE Complete A-Z List
subjects Adolescent
Adult
Alternative medicine
Antiparasitic agents
Biopsy
Cancer therapies
Carcinoma, Squamous Cell - etiology
Carcinoma, Squamous Cell - pathology
Case reports
Female
Humans
Lupus
Lupus Erythematosus, Discoid - complications
Male
Metastasis
Middle Aged
Neoplasm Metastasis
Patients
Skin cancer
Skin Neoplasms - etiology
Skin Neoplasms - pathology
Sunlight - adverse effects
Ulcers
White people
title High-risk variants of cutaneous squamous cell carcinoma in patients with discoid lupus erythematosus: a case series
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