HipA-Triggered Growth Arrest and β-Lactam Tolerance in Escherichia coli Are Mediated by RelA-Dependent ppGpp Synthesis

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Veröffentlicht in:	Journal of Bacteriology 2013-07, Vol.195 (14), p.3173-3182
Hauptverfasser:	Bokinsky, Gregory, Baidoo, Edward E K, Akella, Swetha, Burd, Helcio, Weaver, Daniel, Alonso-Gutierrez, Jorge, García-Martín, Héctor, Lee, Taek Soon, Keasling, Jay D
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acids Anti-Bacterial Agents - metabolism bacteria bacteriophages beta-lactam antibiotics beta-Lactams - metabolism chloramphenicol DNA replication Drug Resistance, Bacterial Escherichia coli Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - growth & development Escherichia coli - metabolism Escherichia coli Proteins - metabolism fermentation Gene Expression Regulation, Bacterial glucose Glucose - metabolism Ligases - metabolism Oxygen - metabolism oxygen consumption protein kinases proteins RNA starvation toxins
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