Molecular Monitoring of Minimal Residual Disease in the Peripheral Blood of Patients with Multiple Myeloma

Abstract The prognostic relevance of minimal residual disease (MRD) in patients with multiple myeloma is still an open question. In bone marrow, the level of residual myeloma cells is associated with treatment outcome, but the role of clonotypic cells in the peripheral blood (PB) for the prognosis o...

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Veröffentlicht in:	Biology of blood and marrow transplantation 2013-07, Vol.19 (7), p.1109-1115
Hauptverfasser:	Korthals, Mark, Sehnke, Nina, Kronenwett, Ralf, Schroeder, Thomas, Strapatsas, Tobias, Kobbe, Guido, Haas, Rainer, Fenk, Roland
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents - therapeutic use beta 2-Microglobulin - blood Biomarkers - blood Female Hematology, Oncology and Palliative Medicine Hemoglobins - analysis Humans IgH-PCR Male Middle Aged Minimal residual disease Molecular Diagnostic Techniques Multiple myeloma Multiple Myeloma - blood Multiple Myeloma - diagnosis Multiple Myeloma - mortality Multiple Myeloma - therapy Neoplasm, Residual - blood Neoplasm, Residual - diagnosis Neoplasm, Residual - mortality Neoplasm, Residual - therapy Peripheral Blood Stem Cell Transplantation Prognosis Real-Time Polymerase Chain Reaction Retrospective Studies Survival Analysis Transplantation, Autologous
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