Cigarette smoke-induced morphological transformation of Bhas 42 cells in vitro

In vitro cell transformation assays detect transformed cells that have acquired the distinct characteristics of malignant cells and thus model one stage of in vivo carcinogenesis. These assays have been proposed as surrogate models for predicting the non-genotoxic carcinogenic potential of chemicals...

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Veröffentlicht in:	Alternatives to laboratory animals 2013-05, Vol.41 (2), p.181-189
Hauptverfasser:	Weisensee, Dirk, Poth, Albrecht, Roemer, Ewald, Conroy, Lynda L, Schlage, Walter K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BALB 3T3 Cells Cell Transformation, Neoplastic Mice Particulate Matter - adverse effects Reproducibility of Results Smoke - adverse effects
Online-Zugang:	Volltext
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