Magnetic resonance imaging of the sacroiliac joints in the early detection of spondyloarthritis: no added value of gadolinium compared with short tau inversion recovery sequence

To investigate the additional value of T1 fat-saturated after gadolinium (T1/Gd) compared with T1 and short tau inversion recovery (STIR) sequence in detecting active lesions of the SI joints typical of axial SpA (axSpA) in a prospective cohort study, the SpondyloArthritis Caught Early (SPACE) cohor...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Rheumatology (Oxford, England) England), 2013-07, Vol.52 (7), p.1220-1224
Hauptverfasser: de Hooge, Manouk, van den Berg, Rosaline, Navarro-Compán, Victoria, van Gaalen, Floris, van der Heijde, Désirée, Huizinga, Tom, Reijnierse, Monique
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1224
container_issue 7
container_start_page 1220
container_title Rheumatology (Oxford, England)
container_volume 52
creator de Hooge, Manouk
van den Berg, Rosaline
Navarro-Compán, Victoria
van Gaalen, Floris
van der Heijde, Désirée
Huizinga, Tom
Reijnierse, Monique
description To investigate the additional value of T1 fat-saturated after gadolinium (T1/Gd) compared with T1 and short tau inversion recovery (STIR) sequence in detecting active lesions of the SI joints typical of axial SpA (axSpA) in a prospective cohort study, the SpondyloArthritis Caught Early (SPACE) cohort, and to assess its influence on final MRI diagnosis of the SI joint (MRI-SIJ) based on the Assessment of Spondyloarthritis International Society (ASAS) definition of active sacroiliitis. Patients in the SPACE cohort received baseline and 3-month follow-up MRI-SIJ with coronal oblique T1, STIR and T1/Gd sequences. Bone marrow oedema (BME), capsulitis/enthesitis and synovitis and active sacroiliitis according to the ASAS definition were evaluated by three blinded readers. A total of 127 patients received an MRI-SIJ at baseline and 67 patients also received an MRI-SIJ at 3 months follow-up since the Gd protocol was added some months after the start of the SPACE project. Twenty-five of the 127 patients (19.7%) with a baseline MRI-SIJ and 14 of 67 patients (20.6%) with a follow-up MRI-SIJ presented BME on the STIR sequence sufficient to fulfill the ASAS definition for a positive MRI-SIJ. In eight patients, additional synovitis and/or capsulitis/enthesitis was observed; however, no additional BME was visualized on T1/Gd. One patient, without clinical diagnosis of axSpA, showed synovitis as an isolated finding. Synovitis and capsulitis/enthesitis are detectable with the administration of Gd. However, they are always observed in the presence of BME. Therefore T1 and STIR sequence alone are sufficient in the MRI assessment that, among others, is used for diagnosing patients with early axSpA.
doi_str_mv 10.1093/rheumatology/ket012
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1370126197</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1370126197</sourcerecordid><originalsourceid>FETCH-LOGICAL-c350t-e3476bcea532b0b525287d0fe227ebe83e04cf3f4aa0918511ef81460dfef8593</originalsourceid><addsrcrecordid>eNpNUctu2zAQJIoGjZvkCwIUPPbihA_JknsrjLYJ4CKX5CysyJVEhyJdkkqhz-ofho6ToKcdYGd2FjOEXHJ2xdlaXocBpxGSt76frx8xMS4-kAUvVmLJpBQf37EoTsnnGHeMsZLL-hM5FbLgNavZgvz7Db3DZBQNGL0Dp5CaEXrjeuo7mgakEVTwxhpQdOeNS5Ea97JACHamGhOqZLw78OPeOz1bDyENwSQTv1HnKWiNmj6BnfBA6kF7a5yZRqr8uIeQl39NGmgcfEg0wZQdnjDEw9GAymc804h_JszvnZOTDmzEi9d5Rh5-_rjf3Cy3d79uN9-3SyVLlpYoi2rVKoRSipa1pShFXWnWoRAVtlhLZIXqZFcAsDWvS86xq3NgTHcZlGt5Rr4e7-6Dz84xNaOJCq0Fh36KDZdVTnzF11WmyiM1BxVjwK7ZhxximBvOmkNXzf9dNceusurLq8HUjqjfNW_lyGcHTZpO</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1370126197</pqid></control><display><type>article</type><title>Magnetic resonance imaging of the sacroiliac joints in the early detection of spondyloarthritis: no added value of gadolinium compared with short tau inversion recovery sequence</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>de Hooge, Manouk ; van den Berg, Rosaline ; Navarro-Compán, Victoria ; van Gaalen, Floris ; van der Heijde, Désirée ; Huizinga, Tom ; Reijnierse, Monique</creator><creatorcontrib>de Hooge, Manouk ; van den Berg, Rosaline ; Navarro-Compán, Victoria ; van Gaalen, Floris ; van der Heijde, Désirée ; Huizinga, Tom ; Reijnierse, Monique</creatorcontrib><description>To investigate the additional value of T1 fat-saturated after gadolinium (T1/Gd) compared with T1 and short tau inversion recovery (STIR) sequence in detecting active lesions of the SI joints typical of axial SpA (axSpA) in a prospective cohort study, the SpondyloArthritis Caught Early (SPACE) cohort, and to assess its influence on final MRI diagnosis of the SI joint (MRI-SIJ) based on the Assessment of Spondyloarthritis International Society (ASAS) definition of active sacroiliitis. Patients in the SPACE cohort received baseline and 3-month follow-up MRI-SIJ with coronal oblique T1, STIR and T1/Gd sequences. Bone marrow oedema (BME), capsulitis/enthesitis and synovitis and active sacroiliitis according to the ASAS definition were evaluated by three blinded readers. A total of 127 patients received an MRI-SIJ at baseline and 67 patients also received an MRI-SIJ at 3 months follow-up since the Gd protocol was added some months after the start of the SPACE project. Twenty-five of the 127 patients (19.7%) with a baseline MRI-SIJ and 14 of 67 patients (20.6%) with a follow-up MRI-SIJ presented BME on the STIR sequence sufficient to fulfill the ASAS definition for a positive MRI-SIJ. In eight patients, additional synovitis and/or capsulitis/enthesitis was observed; however, no additional BME was visualized on T1/Gd. One patient, without clinical diagnosis of axSpA, showed synovitis as an isolated finding. Synovitis and capsulitis/enthesitis are detectable with the administration of Gd. However, they are always observed in the presence of BME. Therefore T1 and STIR sequence alone are sufficient in the MRI assessment that, among others, is used for diagnosing patients with early axSpA.</description><identifier>ISSN: 1462-0324</identifier><identifier>EISSN: 1462-0332</identifier><identifier>DOI: 10.1093/rheumatology/ket012</identifier><identifier>PMID: 23418080</identifier><language>eng</language><publisher>England</publisher><subject>Adult ; Bone Marrow Diseases - diagnosis ; Cohort Studies ; Early Diagnosis ; Edema - diagnosis ; Gadolinium ; Humans ; Magnetic Resonance Imaging - methods ; Prospective Studies ; Sacroiliac Joint - pathology ; Sacroiliitis - diagnosis ; Spondylarthritis - diagnosis ; Spondylarthritis - pathology ; Synovitis - diagnosis ; Young Adult</subject><ispartof>Rheumatology (Oxford, England), 2013-07, Vol.52 (7), p.1220-1224</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c350t-e3476bcea532b0b525287d0fe227ebe83e04cf3f4aa0918511ef81460dfef8593</citedby><cites>FETCH-LOGICAL-c350t-e3476bcea532b0b525287d0fe227ebe83e04cf3f4aa0918511ef81460dfef8593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23418080$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Hooge, Manouk</creatorcontrib><creatorcontrib>van den Berg, Rosaline</creatorcontrib><creatorcontrib>Navarro-Compán, Victoria</creatorcontrib><creatorcontrib>van Gaalen, Floris</creatorcontrib><creatorcontrib>van der Heijde, Désirée</creatorcontrib><creatorcontrib>Huizinga, Tom</creatorcontrib><creatorcontrib>Reijnierse, Monique</creatorcontrib><title>Magnetic resonance imaging of the sacroiliac joints in the early detection of spondyloarthritis: no added value of gadolinium compared with short tau inversion recovery sequence</title><title>Rheumatology (Oxford, England)</title><addtitle>Rheumatology (Oxford)</addtitle><description>To investigate the additional value of T1 fat-saturated after gadolinium (T1/Gd) compared with T1 and short tau inversion recovery (STIR) sequence in detecting active lesions of the SI joints typical of axial SpA (axSpA) in a prospective cohort study, the SpondyloArthritis Caught Early (SPACE) cohort, and to assess its influence on final MRI diagnosis of the SI joint (MRI-SIJ) based on the Assessment of Spondyloarthritis International Society (ASAS) definition of active sacroiliitis. Patients in the SPACE cohort received baseline and 3-month follow-up MRI-SIJ with coronal oblique T1, STIR and T1/Gd sequences. Bone marrow oedema (BME), capsulitis/enthesitis and synovitis and active sacroiliitis according to the ASAS definition were evaluated by three blinded readers. A total of 127 patients received an MRI-SIJ at baseline and 67 patients also received an MRI-SIJ at 3 months follow-up since the Gd protocol was added some months after the start of the SPACE project. Twenty-five of the 127 patients (19.7%) with a baseline MRI-SIJ and 14 of 67 patients (20.6%) with a follow-up MRI-SIJ presented BME on the STIR sequence sufficient to fulfill the ASAS definition for a positive MRI-SIJ. In eight patients, additional synovitis and/or capsulitis/enthesitis was observed; however, no additional BME was visualized on T1/Gd. One patient, without clinical diagnosis of axSpA, showed synovitis as an isolated finding. Synovitis and capsulitis/enthesitis are detectable with the administration of Gd. However, they are always observed in the presence of BME. Therefore T1 and STIR sequence alone are sufficient in the MRI assessment that, among others, is used for diagnosing patients with early axSpA.</description><subject>Adult</subject><subject>Bone Marrow Diseases - diagnosis</subject><subject>Cohort Studies</subject><subject>Early Diagnosis</subject><subject>Edema - diagnosis</subject><subject>Gadolinium</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Prospective Studies</subject><subject>Sacroiliac Joint - pathology</subject><subject>Sacroiliitis - diagnosis</subject><subject>Spondylarthritis - diagnosis</subject><subject>Spondylarthritis - pathology</subject><subject>Synovitis - diagnosis</subject><subject>Young Adult</subject><issn>1462-0324</issn><issn>1462-0332</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNUctu2zAQJIoGjZvkCwIUPPbihA_JknsrjLYJ4CKX5CysyJVEhyJdkkqhz-ofho6ToKcdYGd2FjOEXHJ2xdlaXocBpxGSt76frx8xMS4-kAUvVmLJpBQf37EoTsnnGHeMsZLL-hM5FbLgNavZgvz7Db3DZBQNGL0Dp5CaEXrjeuo7mgakEVTwxhpQdOeNS5Ea97JACHamGhOqZLw78OPeOz1bDyENwSQTv1HnKWiNmj6BnfBA6kF7a5yZRqr8uIeQl39NGmgcfEg0wZQdnjDEw9GAymc804h_JszvnZOTDmzEi9d5Rh5-_rjf3Cy3d79uN9-3SyVLlpYoi2rVKoRSipa1pShFXWnWoRAVtlhLZIXqZFcAsDWvS86xq3NgTHcZlGt5Rr4e7-6Dz84xNaOJCq0Fh36KDZdVTnzF11WmyiM1BxVjwK7ZhxximBvOmkNXzf9dNceusurLq8HUjqjfNW_lyGcHTZpO</recordid><startdate>201307</startdate><enddate>201307</enddate><creator>de Hooge, Manouk</creator><creator>van den Berg, Rosaline</creator><creator>Navarro-Compán, Victoria</creator><creator>van Gaalen, Floris</creator><creator>van der Heijde, Désirée</creator><creator>Huizinga, Tom</creator><creator>Reijnierse, Monique</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201307</creationdate><title>Magnetic resonance imaging of the sacroiliac joints in the early detection of spondyloarthritis: no added value of gadolinium compared with short tau inversion recovery sequence</title><author>de Hooge, Manouk ; van den Berg, Rosaline ; Navarro-Compán, Victoria ; van Gaalen, Floris ; van der Heijde, Désirée ; Huizinga, Tom ; Reijnierse, Monique</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-e3476bcea532b0b525287d0fe227ebe83e04cf3f4aa0918511ef81460dfef8593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Bone Marrow Diseases - diagnosis</topic><topic>Cohort Studies</topic><topic>Early Diagnosis</topic><topic>Edema - diagnosis</topic><topic>Gadolinium</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Prospective Studies</topic><topic>Sacroiliac Joint - pathology</topic><topic>Sacroiliitis - diagnosis</topic><topic>Spondylarthritis - diagnosis</topic><topic>Spondylarthritis - pathology</topic><topic>Synovitis - diagnosis</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Hooge, Manouk</creatorcontrib><creatorcontrib>van den Berg, Rosaline</creatorcontrib><creatorcontrib>Navarro-Compán, Victoria</creatorcontrib><creatorcontrib>van Gaalen, Floris</creatorcontrib><creatorcontrib>van der Heijde, Désirée</creatorcontrib><creatorcontrib>Huizinga, Tom</creatorcontrib><creatorcontrib>Reijnierse, Monique</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Rheumatology (Oxford, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Hooge, Manouk</au><au>van den Berg, Rosaline</au><au>Navarro-Compán, Victoria</au><au>van Gaalen, Floris</au><au>van der Heijde, Désirée</au><au>Huizinga, Tom</au><au>Reijnierse, Monique</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetic resonance imaging of the sacroiliac joints in the early detection of spondyloarthritis: no added value of gadolinium compared with short tau inversion recovery sequence</atitle><jtitle>Rheumatology (Oxford, England)</jtitle><addtitle>Rheumatology (Oxford)</addtitle><date>2013-07</date><risdate>2013</risdate><volume>52</volume><issue>7</issue><spage>1220</spage><epage>1224</epage><pages>1220-1224</pages><issn>1462-0324</issn><eissn>1462-0332</eissn><abstract>To investigate the additional value of T1 fat-saturated after gadolinium (T1/Gd) compared with T1 and short tau inversion recovery (STIR) sequence in detecting active lesions of the SI joints typical of axial SpA (axSpA) in a prospective cohort study, the SpondyloArthritis Caught Early (SPACE) cohort, and to assess its influence on final MRI diagnosis of the SI joint (MRI-SIJ) based on the Assessment of Spondyloarthritis International Society (ASAS) definition of active sacroiliitis. Patients in the SPACE cohort received baseline and 3-month follow-up MRI-SIJ with coronal oblique T1, STIR and T1/Gd sequences. Bone marrow oedema (BME), capsulitis/enthesitis and synovitis and active sacroiliitis according to the ASAS definition were evaluated by three blinded readers. A total of 127 patients received an MRI-SIJ at baseline and 67 patients also received an MRI-SIJ at 3 months follow-up since the Gd protocol was added some months after the start of the SPACE project. Twenty-five of the 127 patients (19.7%) with a baseline MRI-SIJ and 14 of 67 patients (20.6%) with a follow-up MRI-SIJ presented BME on the STIR sequence sufficient to fulfill the ASAS definition for a positive MRI-SIJ. In eight patients, additional synovitis and/or capsulitis/enthesitis was observed; however, no additional BME was visualized on T1/Gd. One patient, without clinical diagnosis of axSpA, showed synovitis as an isolated finding. Synovitis and capsulitis/enthesitis are detectable with the administration of Gd. However, they are always observed in the presence of BME. Therefore T1 and STIR sequence alone are sufficient in the MRI assessment that, among others, is used for diagnosing patients with early axSpA.</abstract><cop>England</cop><pmid>23418080</pmid><doi>10.1093/rheumatology/ket012</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1462-0324
ispartof Rheumatology (Oxford, England), 2013-07, Vol.52 (7), p.1220-1224
issn 1462-0324
1462-0332
language eng
recordid cdi_proquest_miscellaneous_1370126197
source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Alma/SFX Local Collection
subjects Adult
Bone Marrow Diseases - diagnosis
Cohort Studies
Early Diagnosis
Edema - diagnosis
Gadolinium
Humans
Magnetic Resonance Imaging - methods
Prospective Studies
Sacroiliac Joint - pathology
Sacroiliitis - diagnosis
Spondylarthritis - diagnosis
Spondylarthritis - pathology
Synovitis - diagnosis
Young Adult
title Magnetic resonance imaging of the sacroiliac joints in the early detection of spondyloarthritis: no added value of gadolinium compared with short tau inversion recovery sequence
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T14%3A55%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Magnetic%20resonance%20imaging%20of%20the%20sacroiliac%20joints%20in%20the%20early%20detection%20of%20spondyloarthritis:%20no%20added%20value%20of%20gadolinium%20compared%20with%20short%20tau%20inversion%20recovery%20sequence&rft.jtitle=Rheumatology%20(Oxford,%20England)&rft.au=de%20Hooge,%20Manouk&rft.date=2013-07&rft.volume=52&rft.issue=7&rft.spage=1220&rft.epage=1224&rft.pages=1220-1224&rft.issn=1462-0324&rft.eissn=1462-0332&rft_id=info:doi/10.1093/rheumatology/ket012&rft_dat=%3Cproquest_cross%3E1370126197%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1370126197&rft_id=info:pmid/23418080&rfr_iscdi=true