Wolbachia uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in Aedes aegypti

The endosymbiont Wolbachia is common among insects and known for the reproductive manipulations it exerts on hosts as well as inhibition of virus replication in their hosts. Recently, we showed that Wolbachia uses host microRNAs to manipulate host gene expression for its efficient maintenance in the...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2013-06, Vol.110 (25), p.10276-10281
Hauptverfasser:	Zhang, Guangmei, Hussain, Mazhar, O'Neill, Scott L., Asgari, Sassan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aedes - genetics Aedes - microbiology Aedes - virology Animal reproduction Animals Biological Sciences Cell Line Cell lines Dengue - microbiology Dengue - transmission Dengue - virology Dengue fever Dengue Virus - genetics Dengue Virus - growth & development Deoxyribonucleic acid DNA DNA (Cytosine-5-)-Methyltransferases - genetics DNA (Cytosine-5-)-Methyltransferases - metabolism Drosophila Eukaryotes Female Gene expression Gene Expression Regulation, Developmental Gene Expression Regulation, Enzymologic Genes Infections Insect Vectors - genetics Insect Vectors - microbiology Insect Vectors - virology MicroRNA MicroRNAs - genetics Mosquitoes Mosquitos Ovary - enzymology Ovary - microbiology Ovary - virology Reverse transcriptase polymerase chain reaction RNA Symbiosis - physiology Virus Replication - physiology Viruses Wolbachia Wolbachia - growth & development Wolbachia - virology
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