Combination of Bioautography with HPTLC-MS/NMR: A Fast Identification of Acetylcholinesterase Inhibitors from Galbanum

ABSTRACT Introduction In the search for new natural compounds with acetylcholinesterase (AChE) inhibitory activity this study focused on galbanum, the oleo gum‐resin from Ferula gummosa Boiss., which had shown AChE inhibitory activity in a screening. Objective The isolation of bioactive compounds fr...

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Veröffentlicht in:	Phytochemical analysis 2013-07, Vol.24 (4), p.395-400
Hauptverfasser:	Adhami, Hamid-Reza, Scherer, Uta, Kaehlig, Hanspeter, Hettich, Timm, Schlotterbeck, Götz, Reich, Eike, Krenn, Liselotte
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase inhibition auraptene Chemical Fractionation - methods Cholinesterase Inhibitors - analysis Cholinesterase Inhibitors - chemistry Cholinesterase Inhibitors - pharmacology Chromatography, High Pressure Liquid - methods Chromatography, Liquid - methods Coumarins - analysis Coumarins - pharmacology Drug Evaluation, Preclinical - methods farnesiferol A Ferula - chemistry Ferula gummosa Boiss HPTLC-MS/NMR Inhibitory Concentration 50 Magnetic Resonance Spectroscopy - methods Mass Spectrometry - methods Molecular Structure Sesquiterpenes - analysis Sesquiterpenes - pharmacology
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