Phosphatidylinositol 4-phosphate 5-kinase β regulates growth cone morphology and Semaphorin 3A-triggered growth cone collapse in mouse dorsal root ganglion neurons

•PIP5Kβ localizes in the growth cone and axon shaft of mouse DRG neurons.•Overexpression of wild type PIP5Kβ in DRG neurons reduces growth cone size.•Overexpression of a kinase-dead PIP5Kβ (PIP5Kβ-KD) increases growth cone size.•Overexpression of PIP5Kβ-KD inhibits Sema3A-induced growth cone collaps...

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