Neoadjuvant treatment for unresectable rectal cancer: An interim analysis of a multicentre randomized study

Abstract Purpose To present an interim analysis of the trial comparing two neoadjuvant therapies for unresectable rectal cancer. Methods Patients with fixed cT3 or cT4 or locally recurrent rectal cancer without distant metastases were randomized to either 5 × 5 Gy and 3 courses of FOLFOX4 (schedule...

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Veröffentlicht in:	Radiotherapy and oncology 2013-05, Vol.107 (2), p.171-177
Hauptverfasser:	Bujko, Krzysztof, Nasierowska-Guttmejer, Anna, Wyrwicz, Lucjan, Malinowska, Małgorzata, Krynski, Jacek, Kosakowska, Ewa, Rutkowski, Andrzej, Pietrzak, Lucyna, Kepka, Lucyna, Radziszewski, Jakub, Olszyna-Serementa, Marta, Bujko, Magdalena, Danek, Anna, Kryj, Mariusz, Wydmanski, Jerzy, Zegarski, Wojciech, Markiewicz, Wlodzimierz, Lesniak, Tadeusz, Zygulski, Ireneusz, Porzuczek-Zuziak, Dorota, Bebenek, Marek, Maciejczyk, Adam, Polkowski, Wojciech, Czeremszynska, Beata, Cieslak-Zeranska, Ewa, Toczko, Zygmunt, Radkowski, Andrzej, Kolodziejski, Leszek, Szczepkowski, Marek, Majewski, Adam, Jankowski, Michal
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Chemoradiotherapy - adverse effects Female Fluorouracil - therapeutic use Hematology, Oncology and Palliative Medicine Humans Leucovorin - therapeutic use Male Middle Aged Neoadjuvant Therapy - adverse effects Organoplatinum Compounds - therapeutic use Preoperative chemoradiation Rectal Neoplasms - pathology Rectal Neoplasms - therapy Unresectable rectal cancer
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