Numerous granulocyte transfusions to a patient with severe aplastic anemia without severe complication

Abstract One of the most important morbidity causes of aplastic anemia is invasive fungal infections. It could not be possible to take control of infection without neutrophils despite the recent developments in the antifungals. In this presented case, a patient with severe aplastic anemia, granulocy...

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Veröffentlicht in:Transfusion and apheresis science 2013-06, Vol.48 (3), p.371-373
Hauptverfasser: Bozkaya, Ikbal Ok, Kara, Abdurrahman, Yarali, Nese, Cagli, Adnan, Turgut, Seda, Tunc, Bahattin
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container_end_page 373
container_issue 3
container_start_page 371
container_title Transfusion and apheresis science
container_volume 48
creator Bozkaya, Ikbal Ok
Kara, Abdurrahman
Yarali, Nese
Cagli, Adnan
Turgut, Seda
Tunc, Bahattin
description Abstract One of the most important morbidity causes of aplastic anemia is invasive fungal infections. It could not be possible to take control of infection without neutrophils despite the recent developments in the antifungals. In this presented case, a patient with severe aplastic anemia, granulocyte transfusion were administered as 46 times because of the presence of widely invasive aspergillosis and resistance. Only fever reaction was observed as a complication of transfusion amongst the other complications such as acute lung damage, alloimmunisation, and graft-versus-host disease. Granulosit transfusions should not be avoided in patients who had an indication for.
doi_str_mv 10.1016/j.transci.2013.04.019
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It could not be possible to take control of infection without neutrophils despite the recent developments in the antifungals. In this presented case, a patient with severe aplastic anemia, granulocyte transfusion were administered as 46 times because of the presence of widely invasive aspergillosis and resistance. Only fever reaction was observed as a complication of transfusion amongst the other complications such as acute lung damage, alloimmunisation, and graft-versus-host disease. 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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Anemia, Aplastic - complications
Anemia, Aplastic - therapy
Aplastic anemia
Aspergillosis - complications
Aspergillosis - therapy
Blood
Blood Component Removal - methods
Children
Complication
Graft vs Host Disease - therapy
Granulocyte transfusion
Granulocytes - cytology
Health technology assessment
Hematology, Oncology and Palliative Medicine
Humans
Infant
Leukocyte Transfusion - adverse effects
Leukocyte Transfusion - methods
Lung Diseases - immunology
Male
Treatment Outcome
title Numerous granulocyte transfusions to a patient with severe aplastic anemia without severe complication
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