Solute transport across the articular surface of injured cartilage

•We study solute transport in injured cartilage using a wide range of solutes.•Diffusivities in injured cartilage increases significantly versus uninjured controls.•Partition coefficients in injured cartilage are mostly unaffected versus controls. Solute transport through extracellular matrix (ECM)...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2013-07, Vol.535 (2), p.241-247
Hauptverfasser:	Chin, Hooi Chuan, Moeini, Mohammad, Quinn, Thomas M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Articular cartilage Biological Transport cartilage Cartilage, Articular - injuries Cartilage, Articular - metabolism Cattle chondroitin sulfate Chondroitin Sulfates - metabolism Contrast Media - metabolism dextran Dextrans - metabolism Diffusion diffusivity Effective diffusivity explants extracellular matrix Femur - injuries Femur - metabolism fluorescein Fluorescein-5-isothiocyanate fluorescence Fluorescent Dyes image analysis In Vitro Techniques insulin Insulin - metabolism iodides Mechanical injury Molecular Weight Partition coefficient partition coefficients physiology sodium Sodium Iodide - metabolism Solute transport solutes X-radiation
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