A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina. e61618

Widespread gene delivery to the retina is an important challenge for the treatment of retinal diseases, such as retinal dystrophies. We and others have recently shown that the intravenous injection of a self-complementary (sc) AAV9 vector can direct efficient cell transduction in the central nervous...

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Veröffentlicht in:PloS one 2013-04, Vol.8 (4)
Hauptverfasser: Bemelmans, Alexis-Pierre, Duque, Sandra, Riviere, Christel, Astord, Stephanie, Desrosiers, Melissa, Marais, Thibault, Sahel, Jose-Alain, Voit, Thomas, Barkats, Martine
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Sprache:eng
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