Calcium influx through L-type Ca sub( v)1.2 Ca super( 2+) channels regulates mandibular development

The identification of a gain-of-function mutation in CACNA1C as the cause of Timothy Syndrome (TS), a rare disorder characterized by cardiac arrhythmias and syndactyly, highlighted unexpected roles for the L-type voltage-gated Ca super( 2+) channel Ca sub( v)1.2 in nonexcitable cells. How abnormal C...

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Veröffentlicht in:	The Journal of clinical investigation 2013-04, Vol.123 (4), p.1638-1638
Hauptverfasser:	Ramachandran, Kapil V, Hennessey, Jessica A, Barnett, Adam S, Yin, Xinhe, Stadt, Harriett A, Foster, Erika, Shah, Raj A, Yazawa, Masayuki, Dolmetsch, Ricardo E, Kirby, Margaret L, Pitt, Geoffrey S
Format:	Artikel
Sprache:	eng
Schlagworte:	Danio rerio
Online-Zugang:	Volltext
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