What has proteomics taught us about Leishmania development?

Leishmania are obligatory intracellular parasitic protozoa that cycle between sand fly mid-gut and phagolysosomes of mammalian macrophages. They have developed genetically programmed changes in gene and protein expression that enable rapid optimization of cell function according to vector and host e...

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Veröffentlicht in:	Parasitology 2012-08, Vol.139 (9), p.1146-1157
Hauptverfasser:	TSIGANKOV, POLINA, GHERARDINI, PIER FEDERICO, HELMER-CITTERICH, MANUELA, ZILBERSTEIN, DAN
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Animals Biological and medical sciences Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation, Developmental General aspects General aspects and techniques. Study of several systematic groups. Models Humans Insect Vectors - parasitology Invertebrates Leishmania Leishmania - genetics Leishmania - growth & development Leishmania - metabolism Leishmaniasis - parasitology Life Cycle Stages Macrophages - parasitology Phagosomes - parasitology Proteomics - methods Protozoan Proteins - genetics Protozoan Proteins - metabolism Psychodidae - parasitology Signal Transduction
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