Association of interleukin-18 gene variants with susceptibility to visceral leishmaniasis in Iranian population

Host resistance to Leishmania infection is mediated by cellular immune responses leading to macrophage activation and parasite killing. Interleukin-18 (IL-18) known as interferon-γ (IFN-γ) inducing factor, stimulates IFN-γ production by T cells. Taking into account the important role of IL-18 in the...

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Veröffentlicht in:	Molecular biology reports 2013-06, Vol.40 (6), p.4009-4014
Hauptverfasser:	Moravej, Ali, Rasouli, Manoochehr, Asaei, Sadaf, Kalani, Mehdi, Mansoori, Yaser
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animal Anatomy Animal Biochemistry Biomedical and Life Sciences Case-Control Studies Child Child, Preschool Female Gene Frequency - genetics Genes Genetic Association Studies Genetic Predisposition to Disease Haplotypes - genetics Histology Humans Infant Interleukin-18 - genetics Iran Leishmania Leishmaniasis, Visceral - genetics Life Sciences Linkage Disequilibrium - genetics Male Morphology Polymerase chain reaction Polymorphism, Single Nucleotide - genetics Population genetics
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