Merkel cell polyomavirus large T antigen is detected in rare cases of nonmelanoma skin cancer

Background Studies of Merkel cell polyomavirus (MCPyV) in nonmelanoma skin cancers (NMSC) other than Merkel cell carcinoma (MCC) produced controversial results. Therefore, we studied the prevalence of MCPyV in basal cell carcinoma (BCC) and in squamous cell carcinoma (SCC). Methods Tissue specimens...

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Veröffentlicht in:	Journal of cutaneous pathology 2013-06, Vol.40 (6), p.543-549
Hauptverfasser:	Mertz, Kirsten D., Paasinen, Aino, Arnold, Andreas, Baumann, Michèle, Offner, Felix, Willi, Niels, Cathomas, Gieri
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antigens, Viral, Tumor - biosynthesis Antigens, Viral, Tumor - genetics Antigens, Viral, Tumor - immunology basal cell carcinoma Carcinoma, Basal Cell - genetics Carcinoma, Basal Cell - immunology Carcinoma, Basal Cell - metabolism Carcinoma, Basal Cell - pathology Carcinoma, Basal Cell - virology Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - immunology Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - virology Female Gene Expression Regulation, Neoplastic - genetics Gene Expression Regulation, Neoplastic - immunology Gene Expression Regulation, Viral - genetics Gene Expression Regulation, Viral - immunology Genome, Viral - genetics Genome, Viral - immunology Humans immunosuppression Male Merkel cell polyomavirus Merkel cell polyomavirus - genetics Merkel cell polyomavirus - immunology Merkel cell polyomavirus - metabolism Middle Aged nonmelanoma skin cancer Polymerase Chain Reaction Polyomavirus Skin Neoplasms - genetics Skin Neoplasms - immunology Skin Neoplasms - metabolism Skin Neoplasms - pathology Skin Neoplasms - virology squamous cell carcinoma
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