Regulation of PCNA–protein interactions for genome stability

Key Points The sliding clamp proliferating cell nuclear antigen (PCNA) has a crucial role as a processivity factor for DNA replication in eukaryotic cells. PCNA provides a central platform for coordinating many replication-associated processes, such as DNA damage repair or bypass, chromatin establis...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature reviews. Molecular cell biology 2013-05, Vol.14 (5), p.269-282
Hauptverfasser:	Mailand, Niels, Gibbs-Seymour, Ian, Bekker-Jensen, Simon
Format:	Artikel
Sprache:	eng
Schlagworte:	81 86 Antigens Biochemistry Biomedical and Life Sciences Cancer Research Cell Biology Chromosome replication Chromosomes Deoxyribonucleic acid Developmental Biology DNA DNA Damage DNA Replication Genetic aspects Genomes Genomic Instability Humans Life Sciences Physiological aspects Proliferating Cell Nuclear Antigen - genetics Proliferating Cell Nuclear Antigen - metabolism Protein Binding Proteins review-article Stem Cells Ubiquitin Yeast
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!