Flow cytometry thresholds of myeloperoxidase detection to discriminate between acute lymphoblastic or myeloblastic leukaemia

Summary The World Health Organization 2008 Classification emphasizes myeloperoxidase (MPO) detection as sufficient for assigning a blast population to the myeloid lineage. Published MPO positivity thresholds are 10% for flow cytometry (FCM) but 3% for cytochemistry. Here we re‐evaluated the FCM‐MPO...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of haematology 2013-05, Vol.161 (4), p.551-555
Hauptverfasser:	Guy, Julien, Antony‐Debré, Iléana, Benayoun, Emmanuel, Arnoux, Isabelle, Fossat, Chantal, Garff‐Tavernier, Magali, Raimbault, Anna, Imbert, Michèle, Maynadié, Marc, Lacombe, Francis, Béné, Marie C, Wagner‐Ballon, Orianne
Format:	Artikel
Sprache:	eng
Schlagworte:	acute leukaemia Adolescent Adult Aged Aged, 80 and over Biological and medical sciences Child Child, Preschool flow cytometry Flow Cytometry - methods Flow Cytometry - standards Hematologic and hematopoietic diseases Humans Infant Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - enzymology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences Middle Aged myeloid leukaemia myeloperoxidase Peroxidase - analysis Peroxidase - metabolism Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis Precursor Cell Lymphoblastic Leukemia-Lymphoma - enzymology Reference Values Retrospective Studies ROC Curve threshold Tumors Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!