Prevalence of CXCR4-tropic viruses in clustered transmission chains at the time of primary HIV-1 infection

During 2003–2010, 555 strains isolated from sexually-infected patients at the time of primary HIV-1 infection (PHI) were characterized. Tree topology revealed that 11.7% of PHIs segregated into transmission clusters. CXCR4-usage was identified in 27 strains (4.9%) and was significantly associated wi...

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Veröffentlicht in:	Clinical microbiology and infection 2013-05, Vol.19 (5), p.E252-E255
Hauptverfasser:	Frange, P., Meyer, L., Ghosn, J., Deveau, C., Goujard, C., Duvivier, C., Tubiana, R., Rouzioux, C., Chaix, M.-L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged CCR5 Cluster Analysis CXCR4 Female HIV Infections - epidemiology HIV Infections - transmission HIV Infections - virology HIV-1 HIV-1 - classification HIV-1 - isolation & purification HIV-1 - physiology Human immunodeficiency virus 1 Humans Male Middle Aged Prevalence primary infection Receptors, CXCR4 - metabolism Receptors, HIV - metabolism transmission clusters Viral Tropism Young Adult
Online-Zugang:	Volltext
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