MicroRNA-214 suppresses osteogenic differentiation of C2C12 myoblast cells by targeting Osterix

Abstract Osterix (Osx) is an osteoblast-specific transcription factor that is essential for osteoblast differentiation and bone formation. Osx-null mice, which exhibit a complete absence of bone formation and arrested osteoblast differentiation, die immediately after birth. However, our understandin...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2013-08, Vol.55 (2), p.487-494
Hauptverfasser:	Shi, Kaikai, Lu, Jianlei, Zhao, Yue, Wang, Lintao, Li, Ji, Qi, Bing, Li, Hongwei, Ma, Changyan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blotting, Western Bone and Bones - cytology Bone and Bones - metabolism C2C12 Cell Differentiation - physiology Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology Mice MicroRNAs - genetics MicroRNAs - metabolism miR-214 Myoblasts - cytology Myoblasts - metabolism Orthopedics Osteogenesis - physiology Osteogenic differentiation Osterix Real-Time Polymerase Chain Reaction Sp7 Transcription Factor Transcription Factors - genetics Transcription Factors - metabolism Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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