Palladium-Catalyzed Addition of Potassium Aryltrifluoroborates to Aliphatic Nitriles: Synthesis of Alkyl Aryl Ketones, Diketone Compounds, and 2‑Arylbenzo[b]furans

A palladium-catalyzed addition of potassium aryltrifluoroborates to aliphatic nitriles has been developed, leading to a wide range of alkyl aryl ketones with moderate to excellent yields. Moreover, several dinitriles (e.g., malononitrile, glutaronitrile, and adiponitrile) were applicable to this pro...

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Veröffentlicht in:Journal of organic chemistry 2013-06, Vol.78 (11), p.5273-5281
Hauptverfasser: Wang, Xingyong, Liu, Miaochang, Xu, Long, Wang, Qingzong, Chen, Jiuxi, Ding, Jinchang, Wu, Huayue
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Sprache:eng
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