A Mechanism-based Pharmacological Evaluation of Efficacy of Trigonella foenum graecum (Fenugreek) Seeds in Regulation of Dyslipidemia and Oxidative Stress in Hyperlipidemic Rats

Alcoholic extract of Trigonella foenum graecum seeds [fenugreek seed extract (FSE)] was studied in triton-induced and high-fat diet–induced hyperlipidemia to evaluate antidyslipidemic effect. Plasma cholesterol (26.19%) and triglycerides (36.6%) were found to be lowered by FSE maximum at a dose of 2...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2013-06, Vol.61 (6), p.505-512
Hauptverfasser:	Chaturvedi, Upma, Shrivastava, Atul, Bhadauria, Smriti, Saxena, Jitendra K, Bhatia, Gitika
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - pharmacology Bile Acids and Salts - metabolism Biological and medical sciences Cholesterol - blood Disease Models, Animal Disorders of blood lipids. Hyperlipoproteinemia Dyslipidemias - prevention & control General and cellular metabolism. Vitamins General pharmacology Hyperlipidemias - prevention & control In Vitro Techniques Lipoprotein Lipase - metabolism Male Medical sciences Metabolic diseases Oxidative Stress - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phosphatidylcholine-Sterol O-Acyltransferase - metabolism Plant Extracts - pharmacology Rats Seeds - chemistry Treatment Outcome Triglycerides - blood Trigonella - chemistry
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