Oxidized phosphatidylcholines in membrane‐level cellular signaling: from biophysics to physiology and molecular pathology

The oxidation of lipids has been shown to impact virtually all cellular processes. The paradigm has been that this involvement is due to interference with the functions of membrane‐associated proteins. It is only recently that methodological advances in molecular‐level detection and identification h...

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Veröffentlicht in:	The FEBS journal 2013-06, Vol.280 (12), p.2806-2816
Hauptverfasser:	Volinsky, Roman, Kinnunen, Paavo K. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid beta-Peptides - metabolism amyloidogenesis Apoptosis Biophysics Cell Membrane Permeability cytotoxic peptides flip‐flop Humans hydrophobic mismatch lipid asymmetry Lipids liquid‐ordered phase Membranes Molecular biology Oxidation-Reduction Oxidative stress oxidized phospholipids phase segregation Phosphatidylcholines - chemistry Phosphatidylcholines - physiology Phospholipids - chemistry Phospholipids - physiology Signal Transduction
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