Frequency of Malignant Neoplasms in 257 Chronic Leg Ulcers
Background Chronic leg ulcers are one of the most common medical conditions and are a substantial source of morbidity. Objectives To investigate the prevalence of skin cancer mimicking leg ulcers. Patients and Methods This observational study included all patients with a clinical diagnosis of chroni...
Gespeichert in:
Veröffentlicht in: | Dermatologic surgery 2013-06, Vol.39 (6), p.849-854 |
---|---|
Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 854 |
---|---|
container_issue | 6 |
container_start_page | 849 |
container_title | Dermatologic surgery |
container_volume | 39 |
creator | Misciali, Cosimo Dika, Emi Fanti, Pier Alessandro Vaccari, Sabina Baraldi, Carlotta Sgubbi, Paola Patrizi, Annalisa |
description | Background
Chronic leg ulcers are one of the most common medical conditions and are a substantial source of morbidity.
Objectives
To investigate the prevalence of skin cancer mimicking leg ulcers.
Patients and Methods
This observational study included all patients with a clinical diagnosis of chronic leg ulcers (CLU) admitted to the Wound Care Unit, Division of Dermatology, University of Bologna, between March 2008 and February 2011. Patients' general health was assessed, and skin biopsy and vascular Doppler of the lower limbs were performed.
Results
Two hundred fifty‐seven patients ages 45 to 98 with CLU were included. Skin biopsies were performed in all patients. Pathologic results showed that 10 patients had ulcerative lesions of neoplastic origin. Surgical excision was performed in all patients with neoplasms. After at least 1 year of follow‐up, no recurrences were observed.
Discussion and Conclusion
Our findings highlight the important role of systematic biopsies in diagnosing ulcerated tumors of the lower legs and indicate a high prevalence of large ulcerated basal cell carcinomas. |
doi_str_mv | 10.1111/dsu.12168 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1365985799</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1365985799</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3258-1d6b93967f9709b83d435d4d79f6070a0fea062f6c3b95d5d5129a497ebf3f653</originalsourceid><addsrcrecordid>eNp1kLtOAzEQRS0EIhAo-AHkEopN_FjbazoUCCAFKCC15fUjLNpHsLNC-XsMG-iYKWaKo6urA8AZRhOcZmpjP8EE82IPHGFG8iwXhO2nHwmeIYbJCBzH-I4QJpKiQzAiNOd5IdgRuJoH99G71mxh5-GjrqtVq9sNfHLdutaxibBqIWECzt5C11YGLtwKLmvjQjwBB17X0Z3u7hgs57evs_ts8Xz3MLteZIYSVmTY8lJSyYWXAsmyoDanzOZWSM-RQBp5pxEnnhtaSmbTppY6l8KVnnrO6BhcDLnr0KWqcaOaKhpX17p1XR8VppzJggkpE3o5oCZ0MQbn1TpUjQ5bhZH6VqWSKvWjKrHnu9i-bJz9I3_dJGA6AJ9V7bb_J6mbl-UQ-QWlgnBk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1365985799</pqid></control><display><type>article</type><title>Frequency of Malignant Neoplasms in 257 Chronic Leg Ulcers</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Journals@Ovid Complete</source><creator>Misciali, Cosimo ; Dika, Emi ; Fanti, Pier Alessandro ; Vaccari, Sabina ; Baraldi, Carlotta ; Sgubbi, Paola ; Patrizi, Annalisa</creator><creatorcontrib>Misciali, Cosimo ; Dika, Emi ; Fanti, Pier Alessandro ; Vaccari, Sabina ; Baraldi, Carlotta ; Sgubbi, Paola ; Patrizi, Annalisa</creatorcontrib><description>Background
Chronic leg ulcers are one of the most common medical conditions and are a substantial source of morbidity.
Objectives
To investigate the prevalence of skin cancer mimicking leg ulcers.
Patients and Methods
This observational study included all patients with a clinical diagnosis of chronic leg ulcers (CLU) admitted to the Wound Care Unit, Division of Dermatology, University of Bologna, between March 2008 and February 2011. Patients' general health was assessed, and skin biopsy and vascular Doppler of the lower limbs were performed.
Results
Two hundred fifty‐seven patients ages 45 to 98 with CLU were included. Skin biopsies were performed in all patients. Pathologic results showed that 10 patients had ulcerative lesions of neoplastic origin. Surgical excision was performed in all patients with neoplasms. After at least 1 year of follow‐up, no recurrences were observed.
Discussion and Conclusion
Our findings highlight the important role of systematic biopsies in diagnosing ulcerated tumors of the lower legs and indicate a high prevalence of large ulcerated basal cell carcinomas.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1111/dsu.12168</identifier><identifier>PMID: 23464875</identifier><language>eng</language><publisher>United States</publisher><subject>Aged ; Aged, 80 and over ; Chronic Disease ; Female ; Humans ; Leg Ulcer - complications ; Leg Ulcer - diagnosis ; Male ; Middle Aged ; Skin Neoplasms - complications ; Skin Neoplasms - diagnosis ; Skin Neoplasms - epidemiology</subject><ispartof>Dermatologic surgery, 2013-06, Vol.39 (6), p.849-854</ispartof><rights>2013 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3258-1d6b93967f9709b83d435d4d79f6070a0fea062f6c3b95d5d5129a497ebf3f653</citedby><cites>FETCH-LOGICAL-c3258-1d6b93967f9709b83d435d4d79f6070a0fea062f6c3b95d5d5129a497ebf3f653</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fdsu.12168$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fdsu.12168$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23464875$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Misciali, Cosimo</creatorcontrib><creatorcontrib>Dika, Emi</creatorcontrib><creatorcontrib>Fanti, Pier Alessandro</creatorcontrib><creatorcontrib>Vaccari, Sabina</creatorcontrib><creatorcontrib>Baraldi, Carlotta</creatorcontrib><creatorcontrib>Sgubbi, Paola</creatorcontrib><creatorcontrib>Patrizi, Annalisa</creatorcontrib><title>Frequency of Malignant Neoplasms in 257 Chronic Leg Ulcers</title><title>Dermatologic surgery</title><addtitle>Dermatol Surg</addtitle><description>Background
Chronic leg ulcers are one of the most common medical conditions and are a substantial source of morbidity.
Objectives
To investigate the prevalence of skin cancer mimicking leg ulcers.
Patients and Methods
This observational study included all patients with a clinical diagnosis of chronic leg ulcers (CLU) admitted to the Wound Care Unit, Division of Dermatology, University of Bologna, between March 2008 and February 2011. Patients' general health was assessed, and skin biopsy and vascular Doppler of the lower limbs were performed.
Results
Two hundred fifty‐seven patients ages 45 to 98 with CLU were included. Skin biopsies were performed in all patients. Pathologic results showed that 10 patients had ulcerative lesions of neoplastic origin. Surgical excision was performed in all patients with neoplasms. After at least 1 year of follow‐up, no recurrences were observed.
Discussion and Conclusion
Our findings highlight the important role of systematic biopsies in diagnosing ulcerated tumors of the lower legs and indicate a high prevalence of large ulcerated basal cell carcinomas.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Chronic Disease</subject><subject>Female</subject><subject>Humans</subject><subject>Leg Ulcer - complications</subject><subject>Leg Ulcer - diagnosis</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Skin Neoplasms - complications</subject><subject>Skin Neoplasms - diagnosis</subject><subject>Skin Neoplasms - epidemiology</subject><issn>1076-0512</issn><issn>1524-4725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kLtOAzEQRS0EIhAo-AHkEopN_FjbazoUCCAFKCC15fUjLNpHsLNC-XsMG-iYKWaKo6urA8AZRhOcZmpjP8EE82IPHGFG8iwXhO2nHwmeIYbJCBzH-I4QJpKiQzAiNOd5IdgRuJoH99G71mxh5-GjrqtVq9sNfHLdutaxibBqIWECzt5C11YGLtwKLmvjQjwBB17X0Z3u7hgs57evs_ts8Xz3MLteZIYSVmTY8lJSyYWXAsmyoDanzOZWSM-RQBp5pxEnnhtaSmbTppY6l8KVnnrO6BhcDLnr0KWqcaOaKhpX17p1XR8VppzJggkpE3o5oCZ0MQbn1TpUjQ5bhZH6VqWSKvWjKrHnu9i-bJz9I3_dJGA6AJ9V7bb_J6mbl-UQ-QWlgnBk</recordid><startdate>201306</startdate><enddate>201306</enddate><creator>Misciali, Cosimo</creator><creator>Dika, Emi</creator><creator>Fanti, Pier Alessandro</creator><creator>Vaccari, Sabina</creator><creator>Baraldi, Carlotta</creator><creator>Sgubbi, Paola</creator><creator>Patrizi, Annalisa</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201306</creationdate><title>Frequency of Malignant Neoplasms in 257 Chronic Leg Ulcers</title><author>Misciali, Cosimo ; Dika, Emi ; Fanti, Pier Alessandro ; Vaccari, Sabina ; Baraldi, Carlotta ; Sgubbi, Paola ; Patrizi, Annalisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3258-1d6b93967f9709b83d435d4d79f6070a0fea062f6c3b95d5d5129a497ebf3f653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Chronic Disease</topic><topic>Female</topic><topic>Humans</topic><topic>Leg Ulcer - complications</topic><topic>Leg Ulcer - diagnosis</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Skin Neoplasms - complications</topic><topic>Skin Neoplasms - diagnosis</topic><topic>Skin Neoplasms - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Misciali, Cosimo</creatorcontrib><creatorcontrib>Dika, Emi</creatorcontrib><creatorcontrib>Fanti, Pier Alessandro</creatorcontrib><creatorcontrib>Vaccari, Sabina</creatorcontrib><creatorcontrib>Baraldi, Carlotta</creatorcontrib><creatorcontrib>Sgubbi, Paola</creatorcontrib><creatorcontrib>Patrizi, Annalisa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Dermatologic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Misciali, Cosimo</au><au>Dika, Emi</au><au>Fanti, Pier Alessandro</au><au>Vaccari, Sabina</au><au>Baraldi, Carlotta</au><au>Sgubbi, Paola</au><au>Patrizi, Annalisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Frequency of Malignant Neoplasms in 257 Chronic Leg Ulcers</atitle><jtitle>Dermatologic surgery</jtitle><addtitle>Dermatol Surg</addtitle><date>2013-06</date><risdate>2013</risdate><volume>39</volume><issue>6</issue><spage>849</spage><epage>854</epage><pages>849-854</pages><issn>1076-0512</issn><eissn>1524-4725</eissn><abstract>Background
Chronic leg ulcers are one of the most common medical conditions and are a substantial source of morbidity.
Objectives
To investigate the prevalence of skin cancer mimicking leg ulcers.
Patients and Methods
This observational study included all patients with a clinical diagnosis of chronic leg ulcers (CLU) admitted to the Wound Care Unit, Division of Dermatology, University of Bologna, between March 2008 and February 2011. Patients' general health was assessed, and skin biopsy and vascular Doppler of the lower limbs were performed.
Results
Two hundred fifty‐seven patients ages 45 to 98 with CLU were included. Skin biopsies were performed in all patients. Pathologic results showed that 10 patients had ulcerative lesions of neoplastic origin. Surgical excision was performed in all patients with neoplasms. After at least 1 year of follow‐up, no recurrences were observed.
Discussion and Conclusion
Our findings highlight the important role of systematic biopsies in diagnosing ulcerated tumors of the lower legs and indicate a high prevalence of large ulcerated basal cell carcinomas.</abstract><cop>United States</cop><pmid>23464875</pmid><doi>10.1111/dsu.12168</doi><tpages>6</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1076-0512 |
ispartof | Dermatologic surgery, 2013-06, Vol.39 (6), p.849-854 |
issn | 1076-0512 1524-4725 |
language | eng |
recordid | cdi_proquest_miscellaneous_1365985799 |
source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Journals@Ovid Complete |
subjects | Aged Aged, 80 and over Chronic Disease Female Humans Leg Ulcer - complications Leg Ulcer - diagnosis Male Middle Aged Skin Neoplasms - complications Skin Neoplasms - diagnosis Skin Neoplasms - epidemiology |
title | Frequency of Malignant Neoplasms in 257 Chronic Leg Ulcers |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T23%3A17%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Frequency%20of%20Malignant%20Neoplasms%20in%20257%20Chronic%20Leg%20Ulcers&rft.jtitle=Dermatologic%20surgery&rft.au=Misciali,%20Cosimo&rft.date=2013-06&rft.volume=39&rft.issue=6&rft.spage=849&rft.epage=854&rft.pages=849-854&rft.issn=1076-0512&rft.eissn=1524-4725&rft_id=info:doi/10.1111/dsu.12168&rft_dat=%3Cproquest_cross%3E1365985799%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1365985799&rft_id=info:pmid/23464875&rfr_iscdi=true |