Frequency of Malignant Neoplasms in 257 Chronic Leg Ulcers

Background Chronic leg ulcers are one of the most common medical conditions and are a substantial source of morbidity. Objectives To investigate the prevalence of skin cancer mimicking leg ulcers. Patients and Methods This observational study included all patients with a clinical diagnosis of chroni...

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Veröffentlicht in:Dermatologic surgery 2013-06, Vol.39 (6), p.849-854
Hauptverfasser: Misciali, Cosimo, Dika, Emi, Fanti, Pier Alessandro, Vaccari, Sabina, Baraldi, Carlotta, Sgubbi, Paola, Patrizi, Annalisa
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container_end_page 854
container_issue 6
container_start_page 849
container_title Dermatologic surgery
container_volume 39
creator Misciali, Cosimo
Dika, Emi
Fanti, Pier Alessandro
Vaccari, Sabina
Baraldi, Carlotta
Sgubbi, Paola
Patrizi, Annalisa
description Background Chronic leg ulcers are one of the most common medical conditions and are a substantial source of morbidity. Objectives To investigate the prevalence of skin cancer mimicking leg ulcers. Patients and Methods This observational study included all patients with a clinical diagnosis of chronic leg ulcers (CLU) admitted to the Wound Care Unit, Division of Dermatology, University of Bologna, between March 2008 and February 2011. Patients' general health was assessed, and skin biopsy and vascular Doppler of the lower limbs were performed. Results Two hundred fifty‐seven patients ages 45 to 98 with CLU were included. Skin biopsies were performed in all patients. Pathologic results showed that 10 patients had ulcerative lesions of neoplastic origin. Surgical excision was performed in all patients with neoplasms. After at least 1 year of follow‐up, no recurrences were observed. Discussion and Conclusion Our findings highlight the important role of systematic biopsies in diagnosing ulcerated tumors of the lower legs and indicate a high prevalence of large ulcerated basal cell carcinomas.
doi_str_mv 10.1111/dsu.12168
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Objectives To investigate the prevalence of skin cancer mimicking leg ulcers. Patients and Methods This observational study included all patients with a clinical diagnosis of chronic leg ulcers (CLU) admitted to the Wound Care Unit, Division of Dermatology, University of Bologna, between March 2008 and February 2011. Patients' general health was assessed, and skin biopsy and vascular Doppler of the lower limbs were performed. Results Two hundred fifty‐seven patients ages 45 to 98 with CLU were included. Skin biopsies were performed in all patients. Pathologic results showed that 10 patients had ulcerative lesions of neoplastic origin. Surgical excision was performed in all patients with neoplasms. After at least 1 year of follow‐up, no recurrences were observed. Discussion and Conclusion Our findings highlight the important role of systematic biopsies in diagnosing ulcerated tumors of the lower legs and indicate a high prevalence of large ulcerated basal cell carcinomas.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1111/dsu.12168</identifier><identifier>PMID: 23464875</identifier><language>eng</language><publisher>United States</publisher><subject>Aged ; Aged, 80 and over ; Chronic Disease ; Female ; Humans ; Leg Ulcer - complications ; Leg Ulcer - diagnosis ; Male ; Middle Aged ; Skin Neoplasms - complications ; Skin Neoplasms - diagnosis ; Skin Neoplasms - epidemiology</subject><ispartof>Dermatologic surgery, 2013-06, Vol.39 (6), p.849-854</ispartof><rights>2013 by the American Society for Dermatologic Surgery, Inc. 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subjects Aged
Aged, 80 and over
Chronic Disease
Female
Humans
Leg Ulcer - complications
Leg Ulcer - diagnosis
Male
Middle Aged
Skin Neoplasms - complications
Skin Neoplasms - diagnosis
Skin Neoplasms - epidemiology
title Frequency of Malignant Neoplasms in 257 Chronic Leg Ulcers
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