One-step modification of various electrode surfaces using diazonium salt compounds and the application of this technology to electrochemical DNA (E-DNA) sensors
In this work, we have demonstrated that 4-carboxy phenyl groups based modification could be performed on different electrodes, such as indium tin oxide (ITO), gold (Au), and glassy carbon electrode (GCE). The electrode modification has been performed through cyclic voltammetry by sweeping the potent...
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| Veröffentlicht in: | Electrochimica acta 2012-08, Vol.76, p.394-403 |
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| container_title | Electrochimica acta |
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| creator | Chung, Da-Jung Oh, Sang-Hyub Komathi, Shanmugasundaram Gopalan, Anantha Iyengar Lee, Kwang- Pill Choi, Seong-Ho |
| description | In this work, we have demonstrated that 4-carboxy phenyl groups based modification could be performed on different electrodes, such as indium tin oxide (ITO), gold (Au), and glassy carbon electrode (GCE). The electrode modification has been performed through cyclic voltammetry by sweeping the potential between +1.0V and −1.0V for ‘n’ number of potential cycles. The 4-carboxyphenyl modification at different electrode surfaces was confirmed by cyclic voltammetry, contact angle measurements, atomic force microscopy, and X-ray photoelectron spectroscopy analysis. Subsequently, the electrochemical DNA sensor (E-DNA sensor) based on the 4-carboxy phenyl modified GCE was fabricated by the immobilization of probe DNA. The fabricated E-DNA sensor can detect the influenza virus (type A). The current density of the E-DNA sensor was also evaluated by cyclicvoltammetry when the probe DNA and target DNA were hybridized. |
| doi_str_mv | 10.1016/j.electacta.2012.05.044 |
| format | Article |
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The current density of the E-DNA sensor was also evaluated by cyclicvoltammetry when the probe DNA and target DNA were hybridized.</description><identifier>ISSN: 0013-4686</identifier><identifier>EISSN: 1873-3859</identifier><identifier>DOI: 10.1016/j.electacta.2012.05.044</identifier><identifier>CODEN: ELCAAV</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Biological and medical sciences ; Biosensors ; Biotechnology ; Chemistry ; Diazonium salt ; E-DNA biosensor ; Electrochemical reduction ; Electrochemistry ; Exact sciences and technology ; Fundamental and applied biological sciences. Psychology ; General and physical chemistry ; Influenza virus ; Influenza virus (type A) ; Methods. Procedures. Technologies ; Various methods and equipments</subject><ispartof>Electrochimica acta, 2012-08, Vol.76, p.394-403</ispartof><rights>2012</rights><rights>2014 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c378t-805f2c244840b16112db214c9317e67d2845159b37cdd8e162a8b3ec715ff50b3</citedby><cites>FETCH-LOGICAL-c378t-805f2c244840b16112db214c9317e67d2845159b37cdd8e162a8b3ec715ff50b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0013468612008109$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26078541$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Chung, Da-Jung</creatorcontrib><creatorcontrib>Oh, Sang-Hyub</creatorcontrib><creatorcontrib>Komathi, Shanmugasundaram</creatorcontrib><creatorcontrib>Gopalan, Anantha Iyengar</creatorcontrib><creatorcontrib>Lee, Kwang- Pill</creatorcontrib><creatorcontrib>Choi, Seong-Ho</creatorcontrib><title>One-step modification of various electrode surfaces using diazonium salt compounds and the application of this technology to electrochemical DNA (E-DNA) sensors</title><title>Electrochimica acta</title><description>In this work, we have demonstrated that 4-carboxy phenyl groups based modification could be performed on different electrodes, such as indium tin oxide (ITO), gold (Au), and glassy carbon electrode (GCE). The electrode modification has been performed through cyclic voltammetry by sweeping the potential between +1.0V and −1.0V for ‘n’ number of potential cycles. The 4-carboxyphenyl modification at different electrode surfaces was confirmed by cyclic voltammetry, contact angle measurements, atomic force microscopy, and X-ray photoelectron spectroscopy analysis. Subsequently, the electrochemical DNA sensor (E-DNA sensor) based on the 4-carboxy phenyl modified GCE was fabricated by the immobilization of probe DNA. The fabricated E-DNA sensor can detect the influenza virus (type A). The current density of the E-DNA sensor was also evaluated by cyclicvoltammetry when the probe DNA and target DNA were hybridized.</description><subject>Biological and medical sciences</subject><subject>Biosensors</subject><subject>Biotechnology</subject><subject>Chemistry</subject><subject>Diazonium salt</subject><subject>E-DNA biosensor</subject><subject>Electrochemical reduction</subject><subject>Electrochemistry</subject><subject>Exact sciences and technology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General and physical chemistry</subject><subject>Influenza virus</subject><subject>Influenza virus (type A)</subject><subject>Methods. Procedures. 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Psychology</topic><topic>General and physical chemistry</topic><topic>Influenza virus</topic><topic>Influenza virus (type A)</topic><topic>Methods. Procedures. Technologies</topic><topic>Various methods and equipments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chung, Da-Jung</creatorcontrib><creatorcontrib>Oh, Sang-Hyub</creatorcontrib><creatorcontrib>Komathi, Shanmugasundaram</creatorcontrib><creatorcontrib>Gopalan, Anantha Iyengar</creatorcontrib><creatorcontrib>Lee, Kwang- Pill</creatorcontrib><creatorcontrib>Choi, Seong-Ho</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><jtitle>Electrochimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chung, Da-Jung</au><au>Oh, Sang-Hyub</au><au>Komathi, Shanmugasundaram</au><au>Gopalan, Anantha Iyengar</au><au>Lee, Kwang- Pill</au><au>Choi, Seong-Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>One-step modification of various electrode surfaces using diazonium salt compounds and the application of this technology to electrochemical DNA (E-DNA) sensors</atitle><jtitle>Electrochimica acta</jtitle><date>2012-08-01</date><risdate>2012</risdate><volume>76</volume><spage>394</spage><epage>403</epage><pages>394-403</pages><issn>0013-4686</issn><eissn>1873-3859</eissn><coden>ELCAAV</coden><abstract>In this work, we have demonstrated that 4-carboxy phenyl groups based modification could be performed on different electrodes, such as indium tin oxide (ITO), gold (Au), and glassy carbon electrode (GCE). The electrode modification has been performed through cyclic voltammetry by sweeping the potential between +1.0V and −1.0V for ‘n’ number of potential cycles. The 4-carboxyphenyl modification at different electrode surfaces was confirmed by cyclic voltammetry, contact angle measurements, atomic force microscopy, and X-ray photoelectron spectroscopy analysis. Subsequently, the electrochemical DNA sensor (E-DNA sensor) based on the 4-carboxy phenyl modified GCE was fabricated by the immobilization of probe DNA. The fabricated E-DNA sensor can detect the influenza virus (type A). The current density of the E-DNA sensor was also evaluated by cyclicvoltammetry when the probe DNA and target DNA were hybridized.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><doi>10.1016/j.electacta.2012.05.044</doi><tpages>10</tpages></addata></record> |
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| ispartof | Electrochimica acta, 2012-08, Vol.76, p.394-403 |
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| source | Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences Biosensors Biotechnology Chemistry Diazonium salt E-DNA biosensor Electrochemical reduction Electrochemistry Exact sciences and technology Fundamental and applied biological sciences. Psychology General and physical chemistry Influenza virus Influenza virus (type A) Methods. Procedures. Technologies Various methods and equipments |
| title | One-step modification of various electrode surfaces using diazonium salt compounds and the application of this technology to electrochemical DNA (E-DNA) sensors |
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