Early and Midterm Outcomes After Endovascular Treatment of Degenerative Aneurysms of the Descending Thoracic Aorta: A Finnish Multicenter Study

Purpose To evaluate results of endovascular stent-graft placement for aneurysms of the descending aorta in 3 Finnish university hospitals during 1998–2010. Methods Among 158 consecutive patients treated with stent-graft placement for disease of the descending thoracic aorta, all 69 patients (58 men;...

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Veröffentlicht in:Journal of endovascular therapy 2013-06, Vol.20 (3), p.257-264
Hauptverfasser: Saari, Petri, Biancari, Fausto, Ihlberg, Leo, Jaakkola, Pekka, Nevala, Terhi, Perälä, Jukka, Roth, Wolf-Dieter, Manninen, Hannu
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container_end_page 264
container_issue 3
container_start_page 257
container_title Journal of endovascular therapy
container_volume 20
creator Saari, Petri
Biancari, Fausto
Ihlberg, Leo
Jaakkola, Pekka
Nevala, Terhi
Perälä, Jukka
Roth, Wolf-Dieter
Manninen, Hannu
description Purpose To evaluate results of endovascular stent-graft placement for aneurysms of the descending aorta in 3 Finnish university hospitals during 1998–2010. Methods Among 158 consecutive patients treated with stent-graft placement for disease of the descending thoracic aorta, all 69 patients (58 men; mean age 71.7 years, range 54–90) with an aneurysm were included in the analysis. Medical records, radiological images, and national death records were collected and analyzed on an intention-to-treat basis. Results The 30-day mortality rate was 3.7% in 54 elective patients and 46.7% in 15 urgently treated acute patients. The paraparesis rate was 4.3%, and the major stroke rate was 4.3% after the operation. There were 4 aneurysm ruptures, all in the urgent group, two of whom had access failure. The other two died despite seemingly good initial results. The mean follow-up was 34.8±29 months. Two late ruptures occurred in patients who were lost to follow-up. In all, 12 type I (10 early, 2 late) and 1 late type III endoleaks were encountered in the observation period. Conclusion Based on our findings, endovascular treatment of aneurysms of the descending aorta is relatively safe. To reduce the risk of postoperative complications, optimal preoperative imaging is mandatory. Postoperative regular imaging controls are indicated for early detection and prompt treatment of late type I or III endoleaks and to reduce the risk of late ruptures.
doi_str_mv 10.1583/12-4203R.1
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Methods Among 158 consecutive patients treated with stent-graft placement for disease of the descending thoracic aorta, all 69 patients (58 men; mean age 71.7 years, range 54–90) with an aneurysm were included in the analysis. Medical records, radiological images, and national death records were collected and analyzed on an intention-to-treat basis. Results The 30-day mortality rate was 3.7% in 54 elective patients and 46.7% in 15 urgently treated acute patients. The paraparesis rate was 4.3%, and the major stroke rate was 4.3% after the operation. There were 4 aneurysm ruptures, all in the urgent group, two of whom had access failure. The other two died despite seemingly good initial results. The mean follow-up was 34.8±29 months. Two late ruptures occurred in patients who were lost to follow-up. In all, 12 type I (10 early, 2 late) and 1 late type III endoleaks were encountered in the observation period. Conclusion Based on our findings, endovascular treatment of aneurysms of the descending aorta is relatively safe. To reduce the risk of postoperative complications, optimal preoperative imaging is mandatory. Postoperative regular imaging controls are indicated for early detection and prompt treatment of late type I or III endoleaks and to reduce the risk of late ruptures.</description><identifier>ISSN: 1526-6028</identifier><identifier>EISSN: 1545-1550</identifier><identifier>DOI: 10.1583/12-4203R.1</identifier><identifier>PMID: 23731293</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Aged ; Aged, 80 and over ; Aneurysms ; Aortic Aneurysm, Thoracic - surgery ; Blood Vessel Prosthesis ; Confidence intervals ; Endovascular Procedures ; Female ; Hospitalization ; Hospitals ; Humans ; Ischemia ; Male ; Medical imaging ; Middle Aged ; Mortality ; Prostheses ; Retrospective Studies ; Statistical methods ; Stents ; Studies ; Success ; Time Factors ; Treatment Outcome ; Veins &amp; arteries</subject><ispartof>Journal of endovascular therapy, 2013-06, Vol.20 (3), p.257-264</ispartof><rights>2013 International Society of Endovascular Specialists</rights><rights>Copyright Allen Press Publishing Services Jun 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-e6e73e74b374c25633db21c6a19fecc183f9126725d9094ecba0528bfe0361983</citedby><cites>FETCH-LOGICAL-c347t-e6e73e74b374c25633db21c6a19fecc183f9126725d9094ecba0528bfe0361983</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1583/12-4203R.1$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1583/12-4203R.1$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,778,782,21806,27911,27912,43608,43609</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23731293$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saari, Petri</creatorcontrib><creatorcontrib>Biancari, Fausto</creatorcontrib><creatorcontrib>Ihlberg, Leo</creatorcontrib><creatorcontrib>Jaakkola, Pekka</creatorcontrib><creatorcontrib>Nevala, Terhi</creatorcontrib><creatorcontrib>Perälä, Jukka</creatorcontrib><creatorcontrib>Roth, Wolf-Dieter</creatorcontrib><creatorcontrib>Manninen, Hannu</creatorcontrib><title>Early and Midterm Outcomes After Endovascular Treatment of Degenerative Aneurysms of the Descending Thoracic Aorta: A Finnish Multicenter Study</title><title>Journal of endovascular therapy</title><addtitle>J Endovasc Ther</addtitle><description>Purpose To evaluate results of endovascular stent-graft placement for aneurysms of the descending aorta in 3 Finnish university hospitals during 1998–2010. Methods Among 158 consecutive patients treated with stent-graft placement for disease of the descending thoracic aorta, all 69 patients (58 men; mean age 71.7 years, range 54–90) with an aneurysm were included in the analysis. Medical records, radiological images, and national death records were collected and analyzed on an intention-to-treat basis. Results The 30-day mortality rate was 3.7% in 54 elective patients and 46.7% in 15 urgently treated acute patients. The paraparesis rate was 4.3%, and the major stroke rate was 4.3% after the operation. There were 4 aneurysm ruptures, all in the urgent group, two of whom had access failure. The other two died despite seemingly good initial results. The mean follow-up was 34.8±29 months. Two late ruptures occurred in patients who were lost to follow-up. In all, 12 type I (10 early, 2 late) and 1 late type III endoleaks were encountered in the observation period. 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arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saari, Petri</creatorcontrib><creatorcontrib>Biancari, Fausto</creatorcontrib><creatorcontrib>Ihlberg, Leo</creatorcontrib><creatorcontrib>Jaakkola, Pekka</creatorcontrib><creatorcontrib>Nevala, Terhi</creatorcontrib><creatorcontrib>Perälä, Jukka</creatorcontrib><creatorcontrib>Roth, Wolf-Dieter</creatorcontrib><creatorcontrib>Manninen, Hannu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; 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Methods Among 158 consecutive patients treated with stent-graft placement for disease of the descending thoracic aorta, all 69 patients (58 men; mean age 71.7 years, range 54–90) with an aneurysm were included in the analysis. Medical records, radiological images, and national death records were collected and analyzed on an intention-to-treat basis. Results The 30-day mortality rate was 3.7% in 54 elective patients and 46.7% in 15 urgently treated acute patients. The paraparesis rate was 4.3%, and the major stroke rate was 4.3% after the operation. There were 4 aneurysm ruptures, all in the urgent group, two of whom had access failure. The other two died despite seemingly good initial results. The mean follow-up was 34.8±29 months. Two late ruptures occurred in patients who were lost to follow-up. In all, 12 type I (10 early, 2 late) and 1 late type III endoleaks were encountered in the observation period. Conclusion Based on our findings, endovascular treatment of aneurysms of the descending aorta is relatively safe. To reduce the risk of postoperative complications, optimal preoperative imaging is mandatory. Postoperative regular imaging controls are indicated for early detection and prompt treatment of late type I or III endoleaks and to reduce the risk of late ruptures.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>23731293</pmid><doi>10.1583/12-4203R.1</doi><tpages>8</tpages></addata></record>
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subjects Aged
Aged, 80 and over
Aneurysms
Aortic Aneurysm, Thoracic - surgery
Blood Vessel Prosthesis
Confidence intervals
Endovascular Procedures
Female
Hospitalization
Hospitals
Humans
Ischemia
Male
Medical imaging
Middle Aged
Mortality
Prostheses
Retrospective Studies
Statistical methods
Stents
Studies
Success
Time Factors
Treatment Outcome
Veins & arteries
title Early and Midterm Outcomes After Endovascular Treatment of Degenerative Aneurysms of the Descending Thoracic Aorta: A Finnish Multicenter Study
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