Birth defects after incestuous mating: Calculating the probability of causality and reflecting on the desirability of genetic testing
Abstract In this short communication we (1) show that, despite the rarity of autosomal recessive inheritance, primary congenital hydrocephalus in a girl stemming from father-daughter incest is most likely due to the incestuous union of her parents, and (2) reflect on the question, among others, whet...
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| Veröffentlicht in: | European journal of medical genetics 2013-05, Vol.56 (5), p.243-244 |
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| container_title | European journal of medical genetics |
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| creator | ten Kate, Leo P Rath, Matthias Felbor, Ute Frints, Suzanna M.G |
| description | Abstract In this short communication we (1) show that, despite the rarity of autosomal recessive inheritance, primary congenital hydrocephalus in a girl stemming from father-daughter incest is most likely due to the incestuous union of her parents, and (2) reflect on the question, among others, whether actual genetic work-up to support victim indemnification is ever in the interest of the child. |
| doi_str_mv | 10.1016/j.ejmg.2013.02.007 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1769-7212 |
| ispartof | European journal of medical genetics, 2013-05, Vol.56 (5), p.243-244 |
| issn | 1769-7212 1878-0849 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Child Child Abuse, Sexual - diagnosis Congenital hydrocephalus Consanguinity Desirability of testing Fathers Female Genetic Loci Genetic Testing - methods Humans Hydrocephalus - genetics Hydrocephalus - pathology Incest Medical Education Nuclear Family Probability Victim indemnification |
| title | Birth defects after incestuous mating: Calculating the probability of causality and reflecting on the desirability of genetic testing |
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