Poor outcome of HIV-infected patients with plasmablastic lymphoma: results from the German AIDS-related lymphoma cohort study
Out of 302 AIDS-related lymphoma (ARL) patients enrolled in the German ARL cohort study, 18 patients had plasmablastic lymphoma (PBL). Twelve out of 18 patients (67%) have died with a median survival of 4 months (range 0-11 months). In univariate analysis, an intermediate or high international progn...
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| Veröffentlicht in: | AIDS (London) 2013-03, Vol.27 (5), p.842-845 |
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| container_title | AIDS (London) |
| container_volume | 27 |
| creator | Schommers, Philipp Wyen, Christoph Hentrich, Marcus Gillor, Daniel Zoufaly, Alexander Jensen, Bjoern Bogner, Johannes R Thoden, Jan Wasmuth, Jan C Fätkenheuer, Gerd Hoffmann, Christian |
| description | Out of 302 AIDS-related lymphoma (ARL) patients enrolled in the German ARL cohort study, 18 patients had plasmablastic lymphoma (PBL). Twelve out of 18 patients (67%) have died with a median survival of 4 months (range 0-11 months). In univariate analysis, an intermediate or high international prognostic index score was associated with a significantly lower overall survival and progression-free survival. The predominant cause of death was progressive lymphoma (67%). Our data indicate that the outcome of AIDS-related PBL is still very poor. |
| doi_str_mv | 10.1097/QAD.0b013e32835e069d |
| format | Article |
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Twelve out of 18 patients (67%) have died with a median survival of 4 months (range 0-11 months). In univariate analysis, an intermediate or high international prognostic index score was associated with a significantly lower overall survival and progression-free survival. The predominant cause of death was progressive lymphoma (67%). Our data indicate that the outcome of AIDS-related PBL is still very poor.</abstract><cop>England</cop><pmid>23574794</pmid><doi>10.1097/QAD.0b013e32835e069d</doi><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete |
| subjects | Adult Aged AIDS/HIV Analysis of Variance Antineoplastic Combined Chemotherapy Protocols - therapeutic use Antiretroviral Therapy, Highly Active - methods Cohort Studies Germany HIV Infections - complications HIV Infections - drug therapy HIV Infections - mortality Humans Lymphoma, AIDS-Related - drug therapy Lymphoma, AIDS-Related - etiology Lymphoma, AIDS-Related - mortality Lymphoma, Non-Hodgkin - drug therapy Lymphoma, Non-Hodgkin - etiology Lymphoma, Non-Hodgkin - mortality Male Middle Aged Prognosis Prospective Studies Severity of Illness Index |
| title | Poor outcome of HIV-infected patients with plasmablastic lymphoma: results from the German AIDS-related lymphoma cohort study |
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