Regulation of adipocyte differentiation of 3T3-L1 cells by PDZRN3

PDZRN3, a member of the PDZRN (or LNX) family of proteins, is essential for the differentiation of mesenchymal stem cells into myotubes, but it plays an inhibitory role in the differentiation of these cells into osteoblasts. Given that mesenchymal stem cells also differentiate into adipocytes, we ex...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2013-06, Vol.304 (11), p.C1091-C1097
Hauptverfasser:	Honda, Takeshi, Ishii, Aiko, Inui, Makoto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - metabolism Adipogenesis - physiology Animals Carrier Proteins - metabolism CCAAT-Enhancer-Binding Protein-beta - metabolism Cell Differentiation - physiology Cell Line Gene expression Gene Expression Regulation - physiology Immunoblotting Immunoprecipitation Mice Phosphorylation Physiology PPAR gamma - metabolism Proteins Reverse Transcriptase Polymerase Chain Reaction Ribonucleic acid RNA Signal Transduction - physiology STAT5 Transcription Factor - metabolism Stem cells Ubiquitin-Protein Ligases - metabolism
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