Ototoxicity associated with cis‐platinum in three chemotherapy multi‐drug regimens

Hearing threshold differences postcis‐platinum, relative to precis‐platinum levels, were studied in 21 men from a Veterans Administration Medical Center. These patients had previously untreated advanced epidermoid cancers of the head and neck. Each patient received one of three drug combinations: (1...

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Veröffentlicht in:	Cancer 1983-02, Vol.51 (4), p.610-613
Hauptverfasser:	Fleming, Susan M., Peters, Gilmour M., Weaver, Arthur W., Al‐Sarraf, Muhyi, Schumacher, Marie E., Carey, Mary K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Agents - administration & dosage Cisplatin - administration & dosage Cisplatin - adverse effects Dose-Response Relationship, Drug Drug Synergism Drug Therapy, Combination Head and Neck Neoplasms - drug therapy Hearing Loss - chemically induced Hearing Loss, High-Frequency - chemically induced Hearing Tests Humans Male Middle Aged
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