Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

The combination of a direct electron-detection camera that can count individual electrons and an algorithm for correcting for beam-induced motion in cryo-EM will facilitate determination of three-dimensional structures of smaller, lower-symmetry macromolecular complexes to higher resolution than pre...

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Veröffentlicht in:Nature methods 2013-06, Vol.10 (6), p.584-590
Hauptverfasser: Li, Xueming, Mooney, Paul, Zheng, Shawn, Booth, Christopher R, Braunfeld, Michael B, Gubbens, Sander, Agard, David A, Cheng, Yifan
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Sprache:eng
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