A synthetic approach to GFP chromophore analogs from 3-azidocinnamates. Role of methyl rotors in chromophore photophysics

We have suggested a novel combinatorial approach for synthesis of otherwise inaccessible GFP chromophore analogs, and studied the influence of aliphatic substituents on their pH-dependent spectral properties. We found that the demethylation at C or N positions of the imidazolone ring leads to a decr...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2013-01, Vol.49 (51), p.5778-5780
Hauptverfasser:	Baranov, Mikhail S, Solntsev, Kyril M, Lukyanov, Konstantin A, Yampolsky, Ilia V
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalysis Cinnamates - chemistry Green Fluorescent Proteins - chemistry Hydrogen-Ion Concentration Imidazoles - chemistry Isomerism Kinetics Temperature
Online-Zugang:	Volltext
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