Establishment and validation of analytical reference panels for the standardization of quantitative BCR-ABL1 measurements on the international scale

Current guidelines for managing Philadelphia-positive chronic myeloid leukemia include monitoring the expression of the BCR-ABL1 (breakpoint cluster region/c-abl oncogene 1, non-receptor tyrosine kinase) fusion gene by quantitative reverse-transcription PCR (RT-qPCR). Our goal was to establish and v...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2013-06, Vol.59 (6), p.938-948
Hauptverfasser:	White, Helen E, Hedges, John, Bendit, Israel, Branford, Susan, Colomer, Dolors, Hochhaus, Andreas, Hughes, Timothy, Kamel-Reid, Suzanne, Kim, Dong-Wook, Modur, Vijay, Müller, Martin C, Pagnano, Katia B, Pane, Fabrizio, Radich, Jerry, Cross, Nicholas C P, Labourier, Emmanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Agreements Comparative studies Genes, abl Genetic Testing - methods Leukemia Leukemia, Myelogenous, Chronic, BCR-ABL Positive - diagnosis Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - physiopathology Methods Quality standards Reagents Reference Standards Reverse Transcriptase Polymerase Chain Reaction - standards Severity of Illness Index Standardization Studies
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