Dissociation of tolerance and physical dependence after ethanol/chlordiazepoxide intake

The previously-observed attenuation of withdrawal reactions in mice (group B) fed an ethanol diet containing chlordiazepoxide (CDP) was not due to a difference in the rate of disappearance of blood ethanol levels during chronic diet treatment in group B compared to mice which received only the ethan...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1982-01, Vol.17 (6), p.1239-1244
Hauptverfasser:	Chan, Arthur W.K., Schanley, Donna L., Leong, Florence W., Casbeer, Diane
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Withdrawal Delirium - prevention & control Animals Body Temperature Regulation - drug effects Brain - metabolism Chlordiazepoxide Chlordiazepoxide - administration & dosage Drug Tolerance Ethanol Ethanol - administration & dosage Ethanol - blood GABA gamma-Aminobutyric Acid - metabolism Humans Male Mice Mice, Inbred C57BL Physical dependence Psychoses, Alcoholic - prevention & control Sleep Stages - drug effects Tolerance Withdrawal signs
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