The protective effect of Ginkgo biloba extract against experimental cisplatin ototoxicity: animal research using distortion product otoacoustic emissions

Cisplatin, an effective therapeutic agent for various human cancers, has dose-limiting side effects of ototoxicity and nephrotoxicity. Cisplatin ototoxicity is thought to result from increased amounts of toxic free radicals or cell membrane changes leading to increased intracellular calcium content....

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Veröffentlicht in:	Journal of laryngology and otology 2012-11, Vol.126 (11), p.1097-1101
Hauptverfasser:	Cakil, B, Basar, F Suren, Atmaca, S, Cengel, S Kurnaz, Tekat, A, Tanyeri, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics Antineoplastic Agents - adverse effects Auditory system Biological and medical sciences Cisplatin - adverse effects Drug toxicity and drugs side effects treatment Ear, Inner - drug effects Eardrum Ears & hearing Ginkgo biloba Hair Hearing loss Labyrinth Diseases - chemically induced Labyrinth Diseases - prevention & control Main Articles Medical sciences Otoacoustic Emissions, Spontaneous - drug effects Otorhinolaryngology. Stomatology Pharmacology. Drug treatments Plant Extracts - administration & dosage Rats Rats, Wistar Signal to noise ratio Tinnitus Toxicity: respiratory system, ent, stomatology
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