Is genomics bad for you?
The plasticity of the genome complicates genetic causation but should be investigated from a functional perspective. Specific adaptive hypotheses are referenced in the target article, but it is also necessary to explain how the integrity of the genome is maintained despite processes that tend toward...
Gespeichert in:
| Veröffentlicht in: | The Behavioral and brain sciences 2012-10, Vol.35 (5), p.364-365 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 365 |
|---|---|
| container_issue | 5 |
| container_start_page | 364 |
| container_title | The Behavioral and brain sciences |
| container_volume | 35 |
| creator | Dickins, Benjamin J. A. |
| description | The plasticity of the genome complicates genetic causation but should be investigated from a functional perspective. Specific adaptive hypotheses are referenced in the target article, but it is also necessary to explain how the integrity of the genome is maintained despite processes that tend towards its diversification and degradation. These include the accumulation of deleterious changes and intragenomic conflict. |
| doi_str_mv | 10.1017/S0140525X12000994 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1356934931</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1017_S0140525X12000994</cupid><sourcerecordid>1356934931</sourcerecordid><originalsourceid>FETCH-LOGICAL-c401t-5f1c35adad4ef33d4fcb24b1a75435a77a087d62c32411323a78958de0f0290b3</originalsourceid><addsrcrecordid>eNqFkM1Lw0AQxRdRbK3e9SIBL16iOzu7SfYkUvwoFDyo4C1s9qOkNE3dbQ79793QqqCIp4GZ33vDe4ScAb0CCvn1MwVOBRNvwCilUvI9MgSeyRQKJvbJsD-n_X1AjkKYR0ZwIQ_JgCGVAgsxJKeTkMzssm1qHZJKmcS1Ptm03c0xOXBqEezJbo7I6_3dy_gxnT49TMa301RzCutUONAolFGGW4douNMV4xWoXPC4z3NFi9xkTCPjAMhQ5YUUhbHUUSZphSNyufVd-fa9s2FdNnXQdrFQS9t2oQQUmUQuEf5HAURMG7NH9OIHOm87v4xBSpZhziTDjEcKtpT2bQjeunLl60b5TQm07BsufzUcNec7565qrPlSfFYaAdyZqqbytZnZ799_234ApKOAxA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2637292364</pqid></control><display><type>article</type><title>Is genomics bad for you?</title><source>MEDLINE</source><source>Cambridge University Press Journals Complete</source><creator>Dickins, Benjamin J. A.</creator><creatorcontrib>Dickins, Benjamin J. A.</creatorcontrib><description>The plasticity of the genome complicates genetic causation but should be investigated from a functional perspective. Specific adaptive hypotheses are referenced in the target article, but it is also necessary to explain how the integrity of the genome is maintained despite processes that tend towards its diversification and degradation. These include the accumulation of deleterious changes and intragenomic conflict.</description><identifier>ISSN: 0140-525X</identifier><identifier>EISSN: 1469-1825</identifier><identifier>DOI: 10.1017/S0140525X12000994</identifier><identifier>PMID: 23095385</identifier><language>eng</language><publisher>New York, USA: Cambridge University Press</publisher><subject>Adaptation ; Epigenetics ; Extinction ; Female ; Gene expression ; Genetics, Behavioral ; Genomes ; Genomics ; Humans ; Mutation ; Open Peer Commentary ; Population ; Pregnancy</subject><ispartof>The Behavioral and brain sciences, 2012-10, Vol.35 (5), p.364-365</ispartof><rights>Copyright © Cambridge University Press 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c401t-5f1c35adad4ef33d4fcb24b1a75435a77a087d62c32411323a78958de0f0290b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0140525X12000994/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,780,784,27924,27925,55628</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23095385$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dickins, Benjamin J. A.</creatorcontrib><title>Is genomics bad for you?</title><title>The Behavioral and brain sciences</title><addtitle>Behav Brain Sci</addtitle><description>The plasticity of the genome complicates genetic causation but should be investigated from a functional perspective. Specific adaptive hypotheses are referenced in the target article, but it is also necessary to explain how the integrity of the genome is maintained despite processes that tend towards its diversification and degradation. These include the accumulation of deleterious changes and intragenomic conflict.</description><subject>Adaptation</subject><subject>Epigenetics</subject><subject>Extinction</subject><subject>Female</subject><subject>Gene expression</subject><subject>Genetics, Behavioral</subject><subject>Genomes</subject><subject>Genomics</subject><subject>Humans</subject><subject>Mutation</subject><subject>Open Peer Commentary</subject><subject>Population</subject><subject>Pregnancy</subject><issn>0140-525X</issn><issn>1469-1825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkM1Lw0AQxRdRbK3e9SIBL16iOzu7SfYkUvwoFDyo4C1s9qOkNE3dbQ79793QqqCIp4GZ33vDe4ScAb0CCvn1MwVOBRNvwCilUvI9MgSeyRQKJvbJsD-n_X1AjkKYR0ZwIQ_JgCGVAgsxJKeTkMzssm1qHZJKmcS1Ptm03c0xOXBqEezJbo7I6_3dy_gxnT49TMa301RzCutUONAolFGGW4douNMV4xWoXPC4z3NFi9xkTCPjAMhQ5YUUhbHUUSZphSNyufVd-fa9s2FdNnXQdrFQS9t2oQQUmUQuEf5HAURMG7NH9OIHOm87v4xBSpZhziTDjEcKtpT2bQjeunLl60b5TQm07BsufzUcNec7565qrPlSfFYaAdyZqqbytZnZ799_234ApKOAxA</recordid><startdate>201210</startdate><enddate>201210</enddate><creator>Dickins, Benjamin J. A.</creator><general>Cambridge University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7QG</scope></search><sort><creationdate>201210</creationdate><title>Is genomics bad for you?</title><author>Dickins, Benjamin J. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-5f1c35adad4ef33d4fcb24b1a75435a77a087d62c32411323a78958de0f0290b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adaptation</topic><topic>Epigenetics</topic><topic>Extinction</topic><topic>Female</topic><topic>Gene expression</topic><topic>Genetics, Behavioral</topic><topic>Genomes</topic><topic>Genomics</topic><topic>Humans</topic><topic>Mutation</topic><topic>Open Peer Commentary</topic><topic>Population</topic><topic>Pregnancy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dickins, Benjamin J. A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Animal Behavior Abstracts</collection><jtitle>The Behavioral and brain sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dickins, Benjamin J. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is genomics bad for you?</atitle><jtitle>The Behavioral and brain sciences</jtitle><addtitle>Behav Brain Sci</addtitle><date>2012-10</date><risdate>2012</risdate><volume>35</volume><issue>5</issue><spage>364</spage><epage>365</epage><pages>364-365</pages><issn>0140-525X</issn><eissn>1469-1825</eissn><abstract>The plasticity of the genome complicates genetic causation but should be investigated from a functional perspective. Specific adaptive hypotheses are referenced in the target article, but it is also necessary to explain how the integrity of the genome is maintained despite processes that tend towards its diversification and degradation. These include the accumulation of deleterious changes and intragenomic conflict.</abstract><cop>New York, USA</cop><pub>Cambridge University Press</pub><pmid>23095385</pmid><doi>10.1017/S0140525X12000994</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0140-525X |
| ispartof | The Behavioral and brain sciences, 2012-10, Vol.35 (5), p.364-365 |
| issn | 0140-525X 1469-1825 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1356934931 |
| source | MEDLINE; Cambridge University Press Journals Complete |
| subjects | Adaptation Epigenetics Extinction Female Gene expression Genetics, Behavioral Genomes Genomics Humans Mutation Open Peer Commentary Population Pregnancy |
| title | Is genomics bad for you? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T08%3A57%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Is%20genomics%20bad%20for%20you?&rft.jtitle=The%20Behavioral%20and%20brain%20sciences&rft.au=Dickins,%20Benjamin%20J.%20A.&rft.date=2012-10&rft.volume=35&rft.issue=5&rft.spage=364&rft.epage=365&rft.pages=364-365&rft.issn=0140-525X&rft.eissn=1469-1825&rft_id=info:doi/10.1017/S0140525X12000994&rft_dat=%3Cproquest_cross%3E1356934931%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2637292364&rft_id=info:pmid/23095385&rft_cupid=10_1017_S0140525X12000994&rfr_iscdi=true |