Urine toxicology screening in Austrian trauma patients: a prospective study
Introduction The question as to whether the patient consumed drugs prior to the trauma and which drugs were consumed, is of prime importance for the anesthesia required during surgery. However, many patients are unwilling or unable (including those with multiple trauma or impaired consciousness, or...
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| Veröffentlicht in: | Archives of orthopaedic and trauma surgery 2010-07, Vol.130 (7), p.883-887 |
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| creator | Figl, Markus Pelinka, Linda E. Weninger, Patrick Walchetseder, Christoph Mauritz, Walter Hertz, Harald Kroepfl, Albert Schmidhammer, Robert Buchinger, Walter Redl, Heinz |
| description | Introduction
The question as to whether the patient consumed drugs prior to the trauma and which drugs were consumed, is of prime importance for the anesthesia required during surgery. However, many patients are unwilling or unable (including those with multiple trauma or impaired consciousness, or unconscious patients) to answer this question. The purpose of our prospective multicenter study was to collect data about drug consumption in Austria to determine whether drugs are identifiable in the urine of recently injured individuals and to establish the types of drugs consumed.
Materials and methods
This prospective study included severely and moderately injured patients admitted to the Lorenz Boehler Trauma Hospital (Vienna, Austria), the Trauma Hospital Linz (Linz, Austria) and the Department of Trauma Surgery of the General Hospital Horn (Horn, Austria) during an 18-month period (October 2003–March 2005). All patients were suffering from injuries urgently requiring surgery.
Urine samples were gained from all patients immediately after admission. Urinary samples were tested by Immuno-Assay (Triage™ 8 Immuno-Assay, Biosite
®
, San Diego, USA). Urine samples were screened simultaneously for opiates, methadone, cocaine, barbiturates, amphetamines, cannabinoids, benzodiazepines and tricyclic antidepressants.
Results
Our prospective study included a total of 664 patients (320 from Vienna, 193 from the city of Linz, and 151 from Horn). Six hundred and forty-two patients were moderately injured (ISS 16).
Of the 664 patients, 178 (26.8%) tested positive for one or more drugs. The drugs most commonly detected were benzodiazepines (111 patients, 16.7%), cannabinoides (39 patients, 6%), tricyclic antidepressants (28, 4.2%) and opiates (26, 3.9%).
Conclusion
Drug use is widespread in patients presenting to urban trauma centers in Austria.
Physicians should maintain a high index of suspicion that their patients may be intoxicated and should perform drug testing routinely. |
| doi_str_mv | 10.1007/s00402-009-0995-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1356925012</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2261986146</sourcerecordid><originalsourceid>FETCH-LOGICAL-c404t-c346ba27fa510c605be41240e709e5942136e571514e892a34a7dea602e9d56c3</originalsourceid><addsrcrecordid>eNp1kE1LAzEQhoMotlZ_gBdZ8OJldZJNshtvpfiFBS_2HNJ0WlLabE2yYv-9KS0UBE8ZyDPvzDyEXFO4pwD1QwTgwEoAVYJSohQnpE95xctKUXlK-qAqWTYgaI9cxLgEoKxRcE56VDWqaYTok_dJcB6L1P44267axbaINiB65xeF88Wwiyk444sUTLc2xcYkhz7FxyLXoY0btMl9YxFTN9tekrO5WUW8OrwDMnl--hy9luOPl7fRcFxaDjyVtuJyalg9N4KClSCmyCnjgDUoFIozWkkUNRWUY6OYqbipZ2gkMFQzIW01IHf73LzBV4cx6bWLFlcr47HtoqaVkIqJfG1Gb_-gy7YLPm-nGZNZg6RcZoruKZtPigHnehPc2oStpqB3pvXetM6m9c60Frnn5pDcTdc4O3Yc1GaA7YGYv_wCw3H0_6m_mp2Hqw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2261986146</pqid></control><display><type>article</type><title>Urine toxicology screening in Austrian trauma patients: a prospective study</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Figl, Markus ; Pelinka, Linda E. ; Weninger, Patrick ; Walchetseder, Christoph ; Mauritz, Walter ; Hertz, Harald ; Kroepfl, Albert ; Schmidhammer, Robert ; Buchinger, Walter ; Redl, Heinz</creator><creatorcontrib>Figl, Markus ; Pelinka, Linda E. ; Weninger, Patrick ; Walchetseder, Christoph ; Mauritz, Walter ; Hertz, Harald ; Kroepfl, Albert ; Schmidhammer, Robert ; Buchinger, Walter ; Redl, Heinz</creatorcontrib><description>Introduction
The question as to whether the patient consumed drugs prior to the trauma and which drugs were consumed, is of prime importance for the anesthesia required during surgery. However, many patients are unwilling or unable (including those with multiple trauma or impaired consciousness, or unconscious patients) to answer this question. The purpose of our prospective multicenter study was to collect data about drug consumption in Austria to determine whether drugs are identifiable in the urine of recently injured individuals and to establish the types of drugs consumed.
Materials and methods
This prospective study included severely and moderately injured patients admitted to the Lorenz Boehler Trauma Hospital (Vienna, Austria), the Trauma Hospital Linz (Linz, Austria) and the Department of Trauma Surgery of the General Hospital Horn (Horn, Austria) during an 18-month period (October 2003–March 2005). All patients were suffering from injuries urgently requiring surgery.
Urine samples were gained from all patients immediately after admission. Urinary samples were tested by Immuno-Assay (Triage™ 8 Immuno-Assay, Biosite
®
, San Diego, USA). Urine samples were screened simultaneously for opiates, methadone, cocaine, barbiturates, amphetamines, cannabinoids, benzodiazepines and tricyclic antidepressants.
Results
Our prospective study included a total of 664 patients (320 from Vienna, 193 from the city of Linz, and 151 from Horn). Six hundred and forty-two patients were moderately injured (ISS < 16), suffering mostly from injuries to the extremities (504 patients) and 22 patients were severely injured (ISS > 16).
Of the 664 patients, 178 (26.8%) tested positive for one or more drugs. The drugs most commonly detected were benzodiazepines (111 patients, 16.7%), cannabinoides (39 patients, 6%), tricyclic antidepressants (28, 4.2%) and opiates (26, 3.9%).
Conclusion
Drug use is widespread in patients presenting to urban trauma centers in Austria.
Physicians should maintain a high index of suspicion that their patients may be intoxicated and should perform drug testing routinely.</description><identifier>ISSN: 0936-8051</identifier><identifier>EISSN: 1434-3916</identifier><identifier>DOI: 10.1007/s00402-009-0995-5</identifier><identifier>PMID: 19898855</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Austria ; Female ; Humans ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Narcotics ; Orthopedics ; Prospective Studies ; Substance Abuse Detection ; Substance-Related Disorders - urine ; Surgery ; Trauma ; Trauma centers ; Trauma Surgery ; Urine ; Wounds and Injuries - urine ; Young Adult</subject><ispartof>Archives of orthopaedic and trauma surgery, 2010-07, Vol.130 (7), p.883-887</ispartof><rights>Springer-Verlag 2009</rights><rights>Archives of Orthopaedic and Trauma Surgery is a copyright of Springer, (2009). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c404t-c346ba27fa510c605be41240e709e5942136e571514e892a34a7dea602e9d56c3</citedby><cites>FETCH-LOGICAL-c404t-c346ba27fa510c605be41240e709e5942136e571514e892a34a7dea602e9d56c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00402-009-0995-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00402-009-0995-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,778,782,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19898855$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Figl, Markus</creatorcontrib><creatorcontrib>Pelinka, Linda E.</creatorcontrib><creatorcontrib>Weninger, Patrick</creatorcontrib><creatorcontrib>Walchetseder, Christoph</creatorcontrib><creatorcontrib>Mauritz, Walter</creatorcontrib><creatorcontrib>Hertz, Harald</creatorcontrib><creatorcontrib>Kroepfl, Albert</creatorcontrib><creatorcontrib>Schmidhammer, Robert</creatorcontrib><creatorcontrib>Buchinger, Walter</creatorcontrib><creatorcontrib>Redl, Heinz</creatorcontrib><title>Urine toxicology screening in Austrian trauma patients: a prospective study</title><title>Archives of orthopaedic and trauma surgery</title><addtitle>Arch Orthop Trauma Surg</addtitle><addtitle>Arch Orthop Trauma Surg</addtitle><description>Introduction
The question as to whether the patient consumed drugs prior to the trauma and which drugs were consumed, is of prime importance for the anesthesia required during surgery. However, many patients are unwilling or unable (including those with multiple trauma or impaired consciousness, or unconscious patients) to answer this question. The purpose of our prospective multicenter study was to collect data about drug consumption in Austria to determine whether drugs are identifiable in the urine of recently injured individuals and to establish the types of drugs consumed.
Materials and methods
This prospective study included severely and moderately injured patients admitted to the Lorenz Boehler Trauma Hospital (Vienna, Austria), the Trauma Hospital Linz (Linz, Austria) and the Department of Trauma Surgery of the General Hospital Horn (Horn, Austria) during an 18-month period (October 2003–March 2005). All patients were suffering from injuries urgently requiring surgery.
Urine samples were gained from all patients immediately after admission. Urinary samples were tested by Immuno-Assay (Triage™ 8 Immuno-Assay, Biosite
®
, San Diego, USA). Urine samples were screened simultaneously for opiates, methadone, cocaine, barbiturates, amphetamines, cannabinoids, benzodiazepines and tricyclic antidepressants.
Results
Our prospective study included a total of 664 patients (320 from Vienna, 193 from the city of Linz, and 151 from Horn). Six hundred and forty-two patients were moderately injured (ISS < 16), suffering mostly from injuries to the extremities (504 patients) and 22 patients were severely injured (ISS > 16).
Of the 664 patients, 178 (26.8%) tested positive for one or more drugs. The drugs most commonly detected were benzodiazepines (111 patients, 16.7%), cannabinoides (39 patients, 6%), tricyclic antidepressants (28, 4.2%) and opiates (26, 3.9%).
Conclusion
Drug use is widespread in patients presenting to urban trauma centers in Austria.
Physicians should maintain a high index of suspicion that their patients may be intoxicated and should perform drug testing routinely.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Austria</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Narcotics</subject><subject>Orthopedics</subject><subject>Prospective Studies</subject><subject>Substance Abuse Detection</subject><subject>Substance-Related Disorders - urine</subject><subject>Surgery</subject><subject>Trauma</subject><subject>Trauma centers</subject><subject>Trauma Surgery</subject><subject>Urine</subject><subject>Wounds and Injuries - urine</subject><subject>Young Adult</subject><issn>0936-8051</issn><issn>1434-3916</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kE1LAzEQhoMotlZ_gBdZ8OJldZJNshtvpfiFBS_2HNJ0WlLabE2yYv-9KS0UBE8ZyDPvzDyEXFO4pwD1QwTgwEoAVYJSohQnpE95xctKUXlK-qAqWTYgaI9cxLgEoKxRcE56VDWqaYTok_dJcB6L1P44267axbaINiB65xeF88Wwiyk444sUTLc2xcYkhz7FxyLXoY0btMl9YxFTN9tekrO5WUW8OrwDMnl--hy9luOPl7fRcFxaDjyVtuJyalg9N4KClSCmyCnjgDUoFIozWkkUNRWUY6OYqbipZ2gkMFQzIW01IHf73LzBV4cx6bWLFlcr47HtoqaVkIqJfG1Gb_-gy7YLPm-nGZNZg6RcZoruKZtPigHnehPc2oStpqB3pvXetM6m9c60Frnn5pDcTdc4O3Yc1GaA7YGYv_wCw3H0_6m_mp2Hqw</recordid><startdate>20100701</startdate><enddate>20100701</enddate><creator>Figl, Markus</creator><creator>Pelinka, Linda E.</creator><creator>Weninger, Patrick</creator><creator>Walchetseder, Christoph</creator><creator>Mauritz, Walter</creator><creator>Hertz, Harald</creator><creator>Kroepfl, Albert</creator><creator>Schmidhammer, Robert</creator><creator>Buchinger, Walter</creator><creator>Redl, Heinz</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20100701</creationdate><title>Urine toxicology screening in Austrian trauma patients: a prospective study</title><author>Figl, Markus ; Pelinka, Linda E. ; Weninger, Patrick ; Walchetseder, Christoph ; Mauritz, Walter ; Hertz, Harald ; Kroepfl, Albert ; Schmidhammer, Robert ; Buchinger, Walter ; Redl, Heinz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c404t-c346ba27fa510c605be41240e709e5942136e571514e892a34a7dea602e9d56c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Austria</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Narcotics</topic><topic>Orthopedics</topic><topic>Prospective Studies</topic><topic>Substance Abuse Detection</topic><topic>Substance-Related Disorders - urine</topic><topic>Surgery</topic><topic>Trauma</topic><topic>Trauma centers</topic><topic>Trauma Surgery</topic><topic>Urine</topic><topic>Wounds and Injuries - urine</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Figl, Markus</creatorcontrib><creatorcontrib>Pelinka, Linda E.</creatorcontrib><creatorcontrib>Weninger, Patrick</creatorcontrib><creatorcontrib>Walchetseder, Christoph</creatorcontrib><creatorcontrib>Mauritz, Walter</creatorcontrib><creatorcontrib>Hertz, Harald</creatorcontrib><creatorcontrib>Kroepfl, Albert</creatorcontrib><creatorcontrib>Schmidhammer, Robert</creatorcontrib><creatorcontrib>Buchinger, Walter</creatorcontrib><creatorcontrib>Redl, Heinz</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Archives of orthopaedic and trauma surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Figl, Markus</au><au>Pelinka, Linda E.</au><au>Weninger, Patrick</au><au>Walchetseder, Christoph</au><au>Mauritz, Walter</au><au>Hertz, Harald</au><au>Kroepfl, Albert</au><au>Schmidhammer, Robert</au><au>Buchinger, Walter</au><au>Redl, Heinz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Urine toxicology screening in Austrian trauma patients: a prospective study</atitle><jtitle>Archives of orthopaedic and trauma surgery</jtitle><stitle>Arch Orthop Trauma Surg</stitle><addtitle>Arch Orthop Trauma Surg</addtitle><date>2010-07-01</date><risdate>2010</risdate><volume>130</volume><issue>7</issue><spage>883</spage><epage>887</epage><pages>883-887</pages><issn>0936-8051</issn><eissn>1434-3916</eissn><abstract>Introduction
The question as to whether the patient consumed drugs prior to the trauma and which drugs were consumed, is of prime importance for the anesthesia required during surgery. However, many patients are unwilling or unable (including those with multiple trauma or impaired consciousness, or unconscious patients) to answer this question. The purpose of our prospective multicenter study was to collect data about drug consumption in Austria to determine whether drugs are identifiable in the urine of recently injured individuals and to establish the types of drugs consumed.
Materials and methods
This prospective study included severely and moderately injured patients admitted to the Lorenz Boehler Trauma Hospital (Vienna, Austria), the Trauma Hospital Linz (Linz, Austria) and the Department of Trauma Surgery of the General Hospital Horn (Horn, Austria) during an 18-month period (October 2003–March 2005). All patients were suffering from injuries urgently requiring surgery.
Urine samples were gained from all patients immediately after admission. Urinary samples were tested by Immuno-Assay (Triage™ 8 Immuno-Assay, Biosite
®
, San Diego, USA). Urine samples were screened simultaneously for opiates, methadone, cocaine, barbiturates, amphetamines, cannabinoids, benzodiazepines and tricyclic antidepressants.
Results
Our prospective study included a total of 664 patients (320 from Vienna, 193 from the city of Linz, and 151 from Horn). Six hundred and forty-two patients were moderately injured (ISS < 16), suffering mostly from injuries to the extremities (504 patients) and 22 patients were severely injured (ISS > 16).
Of the 664 patients, 178 (26.8%) tested positive for one or more drugs. The drugs most commonly detected were benzodiazepines (111 patients, 16.7%), cannabinoides (39 patients, 6%), tricyclic antidepressants (28, 4.2%) and opiates (26, 3.9%).
Conclusion
Drug use is widespread in patients presenting to urban trauma centers in Austria.
Physicians should maintain a high index of suspicion that their patients may be intoxicated and should perform drug testing routinely.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>19898855</pmid><doi>10.1007/s00402-009-0995-5</doi><tpages>5</tpages></addata></record> |
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| ispartof | Archives of orthopaedic and trauma surgery, 2010-07, Vol.130 (7), p.883-887 |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adolescent Adult Aged Aged, 80 and over Austria Female Humans Male Medicine Medicine & Public Health Middle Aged Narcotics Orthopedics Prospective Studies Substance Abuse Detection Substance-Related Disorders - urine Surgery Trauma Trauma centers Trauma Surgery Urine Wounds and Injuries - urine Young Adult |
| title | Urine toxicology screening in Austrian trauma patients: a prospective study |
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