Physico-chemical properties and structure of oligomycin SC-II, produced by Streptomyces virginiae 17

Under the screening programme for antibiotics with antifungal and immunosuppressive activities, Streptomyces virginiae 17 producing an oligomycin complex was isolated. Separation of the complex by HPLC showed that it contained two components at a ratio of 8:2. The physico-chemical characteristics of...

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Veröffentlicht in:Antibiotiki i himioterapiâ 2012-01, Vol.57 (11-12), p.3-7
Hauptverfasser: Danilenko, A N, Bibikova, M V, Spiridonova, I A, Grammatikova, N E, Katlinskiĭ, A V
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container_issue 11-12
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container_title Antibiotiki i himioterapiâ
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creator Danilenko, A N
Bibikova, M V
Spiridonova, I A
Grammatikova, N E
Katlinskiĭ, A V
description Under the screening programme for antibiotics with antifungal and immunosuppressive activities, Streptomyces virginiae 17 producing an oligomycin complex was isolated. Separation of the complex by HPLC showed that it contained two components at a ratio of 8:2. The physico-chemical characteristics of the components were investigated. The structure of oligomycin was assessed by 13C NMR and 1H NMR.
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title Physico-chemical properties and structure of oligomycin SC-II, produced by Streptomyces virginiae 17
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