Ultrasensitive electrochemical DNA detection based on dual amplification of circular strand-displacement polymerase reaction and hybridization chain reaction

We developed a novel electrochemical strategy for ultrasensitive DNA detection using a dual amplification strategy based on the circular strand-displacement polymerase reaction (CSDPR) and the hybridization chain reaction (HCR). In this assay, hybridization of hairpin-shaped capture DNA to target DN...

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Veröffentlicht in:	Biosensors & bioelectronics 2013-09, Vol.47, p.324-328
Hauptverfasser:	Wang, Cui, Zhou, Hui, Zhu, Wenping, Li, Hongbo, Jiang, Jianhui, Shen, Guoli, Yu, Ruqin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biosensing Techniques Biotechnology Biotin - chemistry Circular strand-displacement polymerase reaction DNA - chemistry DNA - isolation & purification DNA Primers - chemistry Electrochemical DNA sensor Electrochemical Techniques Fundamental and applied biological sciences. Psychology Hybridization chain reaction Limit of Detection Nucleic Acid Hybridization Signal amplification Streptavidin - chemistry
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