Protein accumulation in lung lavage fluid following ozone exposure

Accumulation of protein in lung lavage fluid was used as an indicator of pulmonary damage following exposure of guinea pigs to O 3. Exposure of animals to 510, 1000, or 1960 μg/m 3 (0.26, 0.51, or 1.0 ppm) of O 3 for 72 hr resulted in significantly elevated levels of lavage fluid protein when compar...

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Veröffentlicht in:	Environ. Res.; (United States) 1982-12, Vol.29 (2), p.377-388
Hauptverfasser:	Hu, Ping C., Miller, Frederick J., Daniels, Mary J., Hatch, Gary E., Graham, Judith A., Gardner, Donald E., Selgrade, Maryjane K.
Format:	Artikel
Sprache:	eng
Schlagworte:	560306 - Chemicals Metabolism & Toxicology- Man- (-1987) ANIMALS Ascorbic Acid Deficiency - metabolism Ascorbic Acid Deficiency - pathology BIOLOGICAL EFFECTS BIOLOGICAL MATERIALS BODY BODY FLUIDS Dose-Response Relationship, Drug DOSE-RESPONSE RELATIONSHIPS ELECTROPHORESIS Electrophoresis, Polyacrylamide Gel GUINEA PIGS LAVAGE Lung - drug effects Lung - metabolism LUNGS Male MAMMALS MATERIALS ORGANIC COMPOUNDS ORGANS OZONE Ozone - adverse effects PROTEINS Proteins - metabolism RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RESPIRATORY SYSTEM RODENTS Therapeutic Irrigation Time Factors VERTEBRATES
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