Mechanisms of Intracerebral Lymphoma Growth Delineated in a Syngeneic Mouse Model of Central Nervous System Lymphoma

ABSTRACTPrimary lymphoma of the central nervous system (PCNSL) is defined as lymphoma of the diffuse large B-cell type confined to the CNS. To understand the effects of the CNS microenvironment on the malignant B cells and their interactions with the cells of the target organ, we analyzed a syngenei...

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Veröffentlicht in:	Journal of neuropathology and experimental neurology 2013-04, Vol.72 (4), p.325-336
Hauptverfasser:	Montesinos-Rongen, Manuel, Sánchez-Ruiz, Mónica, Brunn, Anna, Hong, Ke, Bens, Susanne, Perales, Sandra Rodriguez, Cigudosa, Juan C, Siebert, Reiner, Deckert, Martina
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Blood diseases Brain Brain Neoplasms - genetics Brain Neoplasms - pathology Cell Line, Tumor Central Nervous System Neoplasms - genetics Central Nervous System Neoplasms - pathology Colleges & universities Disease Disease Models, Animal Experiments Female Flow cytometry Genotype & phenotype Immune system Lymphocytes Lymphoma Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - pathology Mice Mice, Inbred BALB C Polymerase chain reaction Software Transplantation, Isogeneic Transplants & implants
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