A model for educational simulation of the effect of oxytocin on uterine contractions
Abstract Fetal oxygenation is sometimes compromised due to hyperstimulation of uterine contractions (UC) following labor augmentation with oxytocin. We present a model for educational simulation that incorporates the pharmacokinetic–pharmacodynamic properties of oxytocin, reproducing the effect of t...
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| Veröffentlicht in: | Medical engineering & physics 2013-04, Vol.35 (4), p.524-531 |
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| container_title | Medical engineering & physics |
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| creator | Lobo, Mariana Fernandes Bastos, Luísa Ferreira van Meurs, Willem L Ayres-de-Campos, Diogo |
| description | Abstract Fetal oxygenation is sometimes compromised due to hyperstimulation of uterine contractions (UC) following labor augmentation with oxytocin. We present a model for educational simulation that incorporates the pharmacokinetic–pharmacodynamic properties of oxytocin, reproducing the effect of this drug on UC features. Six UC tracings were generated, reflecting different relevant situations. Three independent experts identified correctly the simulated situations in all tracings and attributed an average realism score of 9.4 (0–10). The model presented for simulation of the effect of oxytocin on UC provides sufficiently realistic results to be used in healthcare education and can easily be adapted to different patients and educational scenarios. |
| doi_str_mv | 10.1016/j.medengphy.2012.06.021 |
| format | Article |
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We present a model for educational simulation that incorporates the pharmacokinetic–pharmacodynamic properties of oxytocin, reproducing the effect of this drug on UC features. Six UC tracings were generated, reflecting different relevant situations. Three independent experts identified correctly the simulated situations in all tracings and attributed an average realism score of 9.4 (0–10). The model presented for simulation of the effect of oxytocin on UC provides sufficiently realistic results to be used in healthcare education and can easily be adapted to different patients and educational scenarios.</description><identifier>ISSN: 1350-4533</identifier><identifier>EISSN: 1873-4030</identifier><identifier>DOI: 10.1016/j.medengphy.2012.06.021</identifier><identifier>PMID: 22835435</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Drugs ; Education, Medical ; Female ; Healthcare education and training ; Humans ; Labor and delivery ; Labor augmentation ; Modeling and simulation ; Models, Biological ; Oxytocin ; Oxytocin - pharmacokinetics ; Oxytocin - pharmacology ; Pharmacodynamics ; Pharmacokinetics ; Pressure ; Radiology ; Uterine activity ; Uterine Contraction - drug effects ; Uterus - drug effects ; Uterus - physiology</subject><ispartof>Medical engineering & physics, 2013-04, Vol.35 (4), p.524-531</ispartof><rights>IPEM</rights><rights>2012 IPEM</rights><rights>Copyright © 2012 IPEM. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-47e10b3236e327eaa349ca9a242c5bf122c57f05c643536da0b3bcde83aeb02a3</citedby><cites>FETCH-LOGICAL-c459t-47e10b3236e327eaa349ca9a242c5bf122c57f05c643536da0b3bcde83aeb02a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1350453312001774$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22835435$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lobo, Mariana Fernandes</creatorcontrib><creatorcontrib>Bastos, Luísa Ferreira</creatorcontrib><creatorcontrib>van Meurs, Willem L</creatorcontrib><creatorcontrib>Ayres-de-Campos, Diogo</creatorcontrib><title>A model for educational simulation of the effect of oxytocin on uterine contractions</title><title>Medical engineering & physics</title><addtitle>Med Eng Phys</addtitle><description>Abstract Fetal oxygenation is sometimes compromised due to hyperstimulation of uterine contractions (UC) following labor augmentation with oxytocin. We present a model for educational simulation that incorporates the pharmacokinetic–pharmacodynamic properties of oxytocin, reproducing the effect of this drug on UC features. Six UC tracings were generated, reflecting different relevant situations. Three independent experts identified correctly the simulated situations in all tracings and attributed an average realism score of 9.4 (0–10). The model presented for simulation of the effect of oxytocin on UC provides sufficiently realistic results to be used in healthcare education and can easily be adapted to different patients and educational scenarios.</description><subject>Drugs</subject><subject>Education, Medical</subject><subject>Female</subject><subject>Healthcare education and training</subject><subject>Humans</subject><subject>Labor and delivery</subject><subject>Labor augmentation</subject><subject>Modeling and simulation</subject><subject>Models, Biological</subject><subject>Oxytocin</subject><subject>Oxytocin - pharmacokinetics</subject><subject>Oxytocin - pharmacology</subject><subject>Pharmacodynamics</subject><subject>Pharmacokinetics</subject><subject>Pressure</subject><subject>Radiology</subject><subject>Uterine activity</subject><subject>Uterine Contraction - drug effects</subject><subject>Uterus - drug effects</subject><subject>Uterus - physiology</subject><issn>1350-4533</issn><issn>1873-4030</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNksFu1DAQhi1ERUvLK4CPXBLGHifeXJBWFRSkShzani3HmVAvSbzYScW-PU639MCpp_HI3z_j-T2MfRBQChD1p105UkfTz_39oZQgZAl1CVK8Ymdio7FQgPA6n7GCQlWIp-xtSjsAUKrGN-xUyg1WCqszdrvlY-ho4H2InLrF2dmHyQ48-XEZHhMeej7fE6e-JzevWfhzmIPz-Wbiy0zRT8RdmOZo3SpIF-ykt0Oid0_xnN19_XJ7-a24_nH1_XJ7XThVNXOhNAloUWJNKDVZi6pxtrFSSVe1vZA56B4qV-enYt3ZDLeuow1aakFaPGcfj3X3MfxeKM1m9MnRMNiJwpJMnl_KBjSKF6BSa6kbUBnVR9TFkFKk3uyjH208GAFmdd_szLP7ZnXfQG2y-1n5_qnJ0mbiWffP7gxsjwBlVx48RZOcp8lR52P21nTBv6DJ5_9quMFP3tnhFx0o7cIS8__liUzKGnOzLsG6A0ICCK0V_gWDFK8k</recordid><startdate>20130401</startdate><enddate>20130401</enddate><creator>Lobo, Mariana Fernandes</creator><creator>Bastos, Luísa Ferreira</creator><creator>van Meurs, Willem L</creator><creator>Ayres-de-Campos, Diogo</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20130401</creationdate><title>A model for educational simulation of the effect of oxytocin on uterine contractions</title><author>Lobo, Mariana Fernandes ; 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We present a model for educational simulation that incorporates the pharmacokinetic–pharmacodynamic properties of oxytocin, reproducing the effect of this drug on UC features. Six UC tracings were generated, reflecting different relevant situations. Three independent experts identified correctly the simulated situations in all tracings and attributed an average realism score of 9.4 (0–10). The model presented for simulation of the effect of oxytocin on UC provides sufficiently realistic results to be used in healthcare education and can easily be adapted to different patients and educational scenarios.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>22835435</pmid><doi>10.1016/j.medengphy.2012.06.021</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Medical engineering & physics, 2013-04, Vol.35 (4), p.524-531 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Drugs Education, Medical Female Healthcare education and training Humans Labor and delivery Labor augmentation Modeling and simulation Models, Biological Oxytocin Oxytocin - pharmacokinetics Oxytocin - pharmacology Pharmacodynamics Pharmacokinetics Pressure Radiology Uterine activity Uterine Contraction - drug effects Uterus - drug effects Uterus - physiology |
| title | A model for educational simulation of the effect of oxytocin on uterine contractions |
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