Increased homologous integration frequency in Yarrowia lipolytica strains defective in non-homologous end-joining

The ascomycetous yeast Yarrowia lipolytica has been established as model system for studies of several research topics as well as for biotechnological processes in the last two decades. However, frequency of heterologous recombination is high in this yeast species, and so knockouts of genes are labo...

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Veröffentlicht in:	Current genetics 2013-05, Vol.59 (1-2), p.63-72
Hauptverfasser:	Kretzschmar, Anne, Otto, Christina, Holz, Martina, Werner, Severine, Hübner, Linda, Barth, Gerold
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology antibiotics Biochemistry Biomedical and Life Sciences Cell Biology DNA DNA End-Joining Repair - genetics Gene Deletion genes homologous recombination Homologous Recombination - genetics Life Sciences Microbial Genetics and Genomics Microbial Sensitivity Tests Microbiology mutagenicity Mutagens - pharmacology Mutation Plant Sciences Proteomics Research Article ultraviolet radiation Yarrowia - classification Yarrowia - drug effects Yarrowia - genetics Yarrowia lipolytica yeasts
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