Comparison of contemporaneous left ventricular ejection fraction (LVEF) obtained from planar gated cardiac blood pool scans (GCBPS) and Tl-201 gated myocardial perfusion scans (MPS) using a novel solid state dedicated cardiac camera
There is limited data on the concordance of left ventricular ejection fraction (LVEF) obtained via solid state dedicated cardiac cameras (SSD) and gated cardiac blood pool scans (GCBPS). This study aimed to examine the agreement of LVEF measured during GCBPS and Tl-201 myocardial perfusion scans (MP...
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| Veröffentlicht in: | Journal of nuclear cardiology 2013-06, Vol.20 (3), p.367-374 |
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| creator | Yap, Kenneth S.K. Cherk, Martin Van Every, Bruce Bailey, Michael Kelly, Michael J. Kalff, Victor |
| description | There is limited data on the concordance of left ventricular ejection fraction (LVEF) obtained via solid state dedicated cardiac cameras (SSD) and gated cardiac blood pool scans (GCBPS). This study aimed to examine the agreement of LVEF measured during GCBPS and Tl-201 myocardial perfusion scans (MPS) using SSD.
Seventy six patients were enrolled. Following stress MPS with 0.8 Mbq/kg (0.022 mCi/kg) Tl-201 and 8-frame gated rest studies after additional 15 Mbq (0.41 mCi) Tl-201, LVEFs were obtained using ECToolbox (ECT) and quantitative gated SPECT (QGS) software. Same day 16-frame planar GCBPS were performed. Interobserver variability was compared and LVEF results were compared using paired t tests, Pearson’s correlation and the differences of the LVEF were plotted against GCBPS values.
For GCBPS, ECT and QGS, the mean (±SD) LVEF was 52% ± 14%, 61% ± 18% and 48% ± 19%, respectively. When compared to GCBPS, ECT and QGS, LVEFs had similar R values of 0.85 and 0.83, respectively, and mean differences [95% limits of agreement (LA)] of −8.6% (−27.4% to +10.2%, P |
| doi_str_mv | 10.1007/s12350-013-9693-3 |
| format | Article |
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Seventy six patients were enrolled. Following stress MPS with 0.8 Mbq/kg (0.022 mCi/kg) Tl-201 and 8-frame gated rest studies after additional 15 Mbq (0.41 mCi) Tl-201, LVEFs were obtained using ECToolbox (ECT) and quantitative gated SPECT (QGS) software. Same day 16-frame planar GCBPS were performed. Interobserver variability was compared and LVEF results were compared using paired t tests, Pearson’s correlation and the differences of the LVEF were plotted against GCBPS values.
For GCBPS, ECT and QGS, the mean (±SD) LVEF was 52% ± 14%, 61% ± 18% and 48% ± 19%, respectively. When compared to GCBPS, ECT and QGS, LVEFs had similar R values of 0.85 and 0.83, respectively, and mean differences [95% limits of agreement (LA)] of −8.6% (−27.4% to +10.2%, P < .001) and 4.2% (−17.2% to +25.6%, P = .001), respectively.
While the LVEF obtained by ECT or QGS demonstrates a statistically significant correlation with GCBPS, they are significantly different and the wide 95% LA suggest that Tl-201 MPS LVEFs derived from either software package are not interchangeable with GCBPS results.</description><identifier>ISSN: 1071-3581</identifier><identifier>EISSN: 1532-6551</identifier><identifier>DOI: 10.1007/s12350-013-9693-3</identifier><identifier>PMID: 23443841</identifier><language>eng</language><publisher>Boston: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cardiology ; Female ; Gamma Cameras ; gated blood pool imaging ; Gated Blood-Pool Imaging - methods ; Humans ; Image Processing, Computer-Assisted ; Imaging ; left ventricular function ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Myocardial Perfusion Imaging - instrumentation ; Myocardial Perfusion Imaging - methods ; Nuclear Medicine ; Observer Variation ; Original Article ; Prospective Studies ; Radiographic Image Interpretation, Computer-Assisted ; Radiology ; radionuclide angiography ; Reproducibility of Results ; SPECT ; Thallium Radioisotopes ; thallium-201 ; Tomography, Emission-Computed, Single-Photon - methods ; Ventricular Function, Left - physiology</subject><ispartof>Journal of nuclear cardiology, 2013-06, Vol.20 (3), p.367-374</ispartof><rights>2013 American Society of Nuclear Cardiology. Published by ELSEVIER INC. All rights reserved.</rights><rights>American Society of Nuclear Cardiology 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c424t-b6a265aeba326a5cc7f2185e156ed3c6b7ecee5b351e08732020e9aebaeed3b83</citedby><cites>FETCH-LOGICAL-c424t-b6a265aeba326a5cc7f2185e156ed3c6b7ecee5b351e08732020e9aebaeed3b83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12350-013-9693-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12350-013-9693-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,27929,27930,41493,42562,51324</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23443841$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yap, Kenneth S.K.</creatorcontrib><creatorcontrib>Cherk, Martin</creatorcontrib><creatorcontrib>Van Every, Bruce</creatorcontrib><creatorcontrib>Bailey, Michael</creatorcontrib><creatorcontrib>Kelly, Michael J.</creatorcontrib><creatorcontrib>Kalff, Victor</creatorcontrib><title>Comparison of contemporaneous left ventricular ejection fraction (LVEF) obtained from planar gated cardiac blood pool scans (GCBPS) and Tl-201 gated myocardial perfusion scans (MPS) using a novel solid state dedicated cardiac camera</title><title>Journal of nuclear cardiology</title><addtitle>J. Nucl. Cardiol</addtitle><addtitle>J Nucl Cardiol</addtitle><description>There is limited data on the concordance of left ventricular ejection fraction (LVEF) obtained via solid state dedicated cardiac cameras (SSD) and gated cardiac blood pool scans (GCBPS). This study aimed to examine the agreement of LVEF measured during GCBPS and Tl-201 myocardial perfusion scans (MPS) using SSD.
Seventy six patients were enrolled. Following stress MPS with 0.8 Mbq/kg (0.022 mCi/kg) Tl-201 and 8-frame gated rest studies after additional 15 Mbq (0.41 mCi) Tl-201, LVEFs were obtained using ECToolbox (ECT) and quantitative gated SPECT (QGS) software. Same day 16-frame planar GCBPS were performed. Interobserver variability was compared and LVEF results were compared using paired t tests, Pearson’s correlation and the differences of the LVEF were plotted against GCBPS values.
For GCBPS, ECT and QGS, the mean (±SD) LVEF was 52% ± 14%, 61% ± 18% and 48% ± 19%, respectively. When compared to GCBPS, ECT and QGS, LVEFs had similar R values of 0.85 and 0.83, respectively, and mean differences [95% limits of agreement (LA)] of −8.6% (−27.4% to +10.2%, P < .001) and 4.2% (−17.2% to +25.6%, P = .001), respectively.
While the LVEF obtained by ECT or QGS demonstrates a statistically significant correlation with GCBPS, they are significantly different and the wide 95% LA suggest that Tl-201 MPS LVEFs derived from either software package are not interchangeable with GCBPS results.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cardiology</subject><subject>Female</subject><subject>Gamma Cameras</subject><subject>gated blood pool imaging</subject><subject>Gated Blood-Pool Imaging - methods</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>Imaging</subject><subject>left ventricular function</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Myocardial Perfusion Imaging - instrumentation</subject><subject>Myocardial Perfusion Imaging - methods</subject><subject>Nuclear Medicine</subject><subject>Observer Variation</subject><subject>Original Article</subject><subject>Prospective Studies</subject><subject>Radiographic Image Interpretation, Computer-Assisted</subject><subject>Radiology</subject><subject>radionuclide angiography</subject><subject>Reproducibility of Results</subject><subject>SPECT</subject><subject>Thallium Radioisotopes</subject><subject>thallium-201</subject><subject>Tomography, Emission-Computed, Single-Photon - methods</subject><subject>Ventricular Function, Left - physiology</subject><issn>1071-3581</issn><issn>1532-6551</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kk1v1DAQhiMEoqXwA7ggS1y2h4A_4nyIU1m1BWkRSBSuluNMVl45drCTlfqP-RlMlAUBh55ieZ5nJhq_WfaS0TeM0uptYlxImlMm8qZsRC4eZedMCp6XUrLHeKYVy4Ws2Vn2LKUDpbQRTfM0O-OiKERdsPPs5zYMo442BU9CT0zwEwxjiNpDmBNx0E_kCH6K1sxORwIHMJNFuI96PWx2369vLkloJ209dFgIAxmd9kjv9YQ3RsfOakNaF0JHxhAcSUb7RDa32_dfvl4S7Tty53JO2ckY7sMqOTJC7Oe0DDo5nxYDb_yeaOLDEbBbcLYjaUKXdNBZ889YoweI-nn2pNcuwYvT9yL7dnN9t_2Q7z7fftxe7XJT8GLK21LzUmpoteCllsZUPWe1BCZL6IQp2woMgGyFZEDrSnDKKTQLD1hva3GRbda-Yww_ZkiTGmwy4Ny6UcXQLBmvOEP09X_oIczR498tVMUKis-IFFspE0NKEXo1RjvoeK8YVUsM1BoDhTFQSwyUQOfVqfPcDtD9MX6_OwJ8BRKW_B7iX6Mf6PpulQD3d7QoJWPBG9x4xFSoLtgH7F8cJNOm</recordid><startdate>20130601</startdate><enddate>20130601</enddate><creator>Yap, Kenneth S.K.</creator><creator>Cherk, Martin</creator><creator>Van Every, Bruce</creator><creator>Bailey, Michael</creator><creator>Kelly, Michael J.</creator><creator>Kalff, Victor</creator><general>Elsevier Inc</general><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20130601</creationdate><title>Comparison of contemporaneous left ventricular ejection fraction (LVEF) obtained from planar gated cardiac blood pool scans (GCBPS) and Tl-201 gated myocardial perfusion scans (MPS) using a novel solid state dedicated cardiac camera</title><author>Yap, Kenneth S.K. ; 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Nucl. Cardiol</stitle><addtitle>J Nucl Cardiol</addtitle><date>2013-06-01</date><risdate>2013</risdate><volume>20</volume><issue>3</issue><spage>367</spage><epage>374</epage><pages>367-374</pages><issn>1071-3581</issn><eissn>1532-6551</eissn><abstract>There is limited data on the concordance of left ventricular ejection fraction (LVEF) obtained via solid state dedicated cardiac cameras (SSD) and gated cardiac blood pool scans (GCBPS). This study aimed to examine the agreement of LVEF measured during GCBPS and Tl-201 myocardial perfusion scans (MPS) using SSD.
Seventy six patients were enrolled. Following stress MPS with 0.8 Mbq/kg (0.022 mCi/kg) Tl-201 and 8-frame gated rest studies after additional 15 Mbq (0.41 mCi) Tl-201, LVEFs were obtained using ECToolbox (ECT) and quantitative gated SPECT (QGS) software. Same day 16-frame planar GCBPS were performed. Interobserver variability was compared and LVEF results were compared using paired t tests, Pearson’s correlation and the differences of the LVEF were plotted against GCBPS values.
For GCBPS, ECT and QGS, the mean (±SD) LVEF was 52% ± 14%, 61% ± 18% and 48% ± 19%, respectively. When compared to GCBPS, ECT and QGS, LVEFs had similar R values of 0.85 and 0.83, respectively, and mean differences [95% limits of agreement (LA)] of −8.6% (−27.4% to +10.2%, P < .001) and 4.2% (−17.2% to +25.6%, P = .001), respectively.
While the LVEF obtained by ECT or QGS demonstrates a statistically significant correlation with GCBPS, they are significantly different and the wide 95% LA suggest that Tl-201 MPS LVEFs derived from either software package are not interchangeable with GCBPS results.</abstract><cop>Boston</cop><pub>Elsevier Inc</pub><pmid>23443841</pmid><doi>10.1007/s12350-013-9693-3</doi><tpages>8</tpages></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Cardiology Female Gamma Cameras gated blood pool imaging Gated Blood-Pool Imaging - methods Humans Image Processing, Computer-Assisted Imaging left ventricular function Male Medicine Medicine & Public Health Middle Aged Myocardial Perfusion Imaging - instrumentation Myocardial Perfusion Imaging - methods Nuclear Medicine Observer Variation Original Article Prospective Studies Radiographic Image Interpretation, Computer-Assisted Radiology radionuclide angiography Reproducibility of Results SPECT Thallium Radioisotopes thallium-201 Tomography, Emission-Computed, Single-Photon - methods Ventricular Function, Left - physiology |
| title | Comparison of contemporaneous left ventricular ejection fraction (LVEF) obtained from planar gated cardiac blood pool scans (GCBPS) and Tl-201 gated myocardial perfusion scans (MPS) using a novel solid state dedicated cardiac camera |
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