Supersolubilization and Amorphization of a Model Basic Drug, Haloperidol, by Interaction with Weak Acids

Purpose To present a novel approach of greatly enhancing aqueous solubility of a model weakly basic drug, haloperidol, by using weak acids that would not form salts with the drug and to attain physically stable form of amorphous drug by drying such aqueous solutions. Method Aqueous solubility of hal...

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