Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation

Interleukin (IL)‐17–producing helper T (Th17) cells serve as a Th subset involved in epithelial cell– and neutrophil‐mediated immune responses against extracellular microbes and in the development of various autoimmune diseases. The differentiation of Th17 cells is controlled by a number of intracel...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2013-03, Vol.1280 (1), p.30-34
Hauptverfasser:	Nagai, Shigenori, Kurebayashi, Yutaka, Koyasu, Shigeo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmune diseases Autoimmune Diseases - immunology Autoimmune Diseases - metabolism Cell Differentiation HIF-1 Humans mTOR Phosphatidylinositol 3-Kinases - metabolism PI3K Proteins Proto-Oncogene Proteins c-akt - metabolism Signal Transduction Th17 Th17 Cells - cytology Th17 Cells - metabolism TOR Serine-Threonine Kinases - metabolism
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