Global metabolomic analysis of heart tissue in a hamster model for dilated cardiomyopathy

Abstract Dilated cardiomyopathy (DCM), a common cause of heart failure, is characterized by cardiac dilation and reduced left ventricular ejection fraction, but the underlying mechanisms remain unclear. To investigate the mechanistic basis, we performed global metabolomic analysis of myocardial tiss...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2013-06, Vol.59, p.76-85
Hauptverfasser:	Maekawa, Keiko, Hirayama, Akiyoshi, Iwata, Yuko, Tajima, Yoko, Nishimaki-Mogami, Tomoko, Sugawara, Shoko, Ueno, Noriko, Abe, Hiroshi, Ishikawa, Masaki, Murayama, Mayumi, Matsuzawa, Yumiko, Nakanishi, Hiroki, Ikeda, Kazutaka, Arita, Makoto, Taguchi, Ryo, Minamino, Naoto, Wakabayashi, Shigeo, Soga, Tomoyoshi, Saito, Yoshiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiomyopathy, Dilated - metabolism Cardiovascular Chromatography, Liquid Cricetinae Dilated cardiomyopathy Disease Models, Animal Electrophoresis, Capillary Hamster model Mass Spectrometry Metabolomics Metabolomics - methods Oxidative stress Oxidative Stress - physiology Phospholipid alteration Phospholipids - metabolism
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