Aberrant TIRAP and MyD88 expression in B-cell chronic lymphocytic leukemia

TIRAP and Myd88 are adaptor proteins for Toll-like receptors-2 and -4 (TLR2/4) which are engaged in transducing the signal to downstream molecules. Several studies have shown the increased role of infection factors in pathogenesis of B cell chronic lymphocytic leukemia (B-CLL). This prompted us to t...

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Veröffentlicht in:	Blood cells, molecules, & diseases molecules, & diseases, 2013-06, Vol.51 (1), p.48-55
Hauptverfasser:	Antosz, Halina, Sajewicz, Joanna, Marzec-Kotarska, Barbara, Dmoszyńska, Anna, Baszak, Jacek, Jargiełło-Baszak, Małgorzata
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antigens, CD - metabolism B-CLL B-Lymphocytes - immunology B-Lymphocytes - metabolism Cells, Cultured Female Gene Expression Regulation, Leukemic Humans IL-6 Immunophenotyping Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Lymphocytic, Chronic, B-Cell - metabolism Lipopolysaccharides - immunology Male Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Middle Aged MyD88 Myeloid Differentiation Factor 88 - genetics Myeloid Differentiation Factor 88 - metabolism Neoplasm Staging Receptors, Interleukin-1 - genetics Receptors, Interleukin-1 - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism TIRAP TLR
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