RNA pulsed dendritic cells: An approach for cancer immunotherapy

Graphical abstract Highlights ► RNA pulsed DC: an improved therapeutic intervention for treating cancers. ► RNA transfections are advantageous over DNA transfection for cancer therapeutics. ► Engineered pH sensitive liposomes improved RNA transfection and sustained expression of tumor antigen.

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Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2013-02, Vol.31 (8), p.1141-1156
Hauptverfasser:	Garg, Neeraj Kumar, Dwivedi, Priya, Prabha, Punit, Tyagi, Rajeev K
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology antigen presentation Antigens Antigens, Neoplasm - genetics Antigens, Neoplasm - immunology Applied microbiology Biological and medical sciences Cancer Cancer immunology Cationic liposome clinical trials Clinical Trials as Topic Dendritic cell dendritic cells Dendritic Cells - immunology Dendritic Cells - metabolism DOTAP Fundamental and applied biological sciences. Psychology Humans immune response Immune surveillance Immune system Immunotherapy Immunotherapy - methods isolation techniques Medical research Medical sciences Messenger RNA Microbiology morbidity mortality Neoplasms - therapy patients Prostate cancer RNA RNA - genetics RNA - metabolism T cell receptors T-lymphocytes Transfection Transfection - methods Tumor associated antigens Tumors Vaccine Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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