Antimicrobial efficacy of a human β-defensin-3 peptide using an Enterococcus faecalis dentine infection model

Aim To assess the antibacterial efficacy of a human β‐defensin‐3 (HBD3) peptide against Enterococcus faecalis biofilms. Methodology Standardized human dentine blocks were infected with E. faecalis ATCC 29212 for 3 weeks. Aqueous calcium hydroxide paste (n = 12, CH), a 2% chlorhexidine gel (n = 12, C...

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Veröffentlicht in:	International endodontic journal 2013-05, Vol.46 (5), p.406-412
Hauptverfasser:	Lee, J.-K., Park, Y.-J., Kum, K.-Y., Han, S. H., Chang, S.-W., Kaufman, B., Jiang, J., Zhu, Q., Safavi, K., Spångberg, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - therapeutic use Anti-Infective Agents, Local - therapeutic use Antimicrobial agents antimicrobial efficacy beta-Defensins - therapeutic use Biofilms - drug effects Calcium Hydroxide - therapeutic use Chlorhexidine - therapeutic use Dental Pulp Cavity - drug effects Dental Pulp Cavity - microbiology Dentin - drug effects Dentin - microbiology dentine block Dentistry E. faecalis biofilms Enterococcus faecalis Enterococcus faecalis - drug effects Gram-Positive Bacterial Infections - drug therapy human β-defensin-3 Humans Humidity Materials Testing Nephelometry and Turbidimetry optical density Root Canal Irrigants - therapeutic use Sodium Chloride Spectrophotometry Temperature Time Factors
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